{"id":"W2944714048","doi":"10.1242/jcs.232249","title":"Proximity-dependent biotinylation mediated by TurboID to identify protein–protein interaction networks in yeast","year":2019,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Biotinylation; Yeast; Computational biology; Protein–protein interaction; Cell biology; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003648597,0.0003725036,0.0004679345,0.0005469225,0.0002618613,0.0005105462,0.0003784445,0.0002535895,0.0008863123],"category_scores_gemma":[0.0004316251,0.0002624742,0.0003974908,0.0004529069,0.0002734814,0.0003163666,0.000686842,0.0006620333,0.0006067919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005621176,"about_ca_system_score_gemma":0.000338737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001374861,"about_ca_topic_score_gemma":0.002864478,"domain_scores_codex":[0.9997754,0.00003918695,0.00002205624,0.00005682949,0.0000780893,0.00002858245],"domain_scores_gemma":[0.9997461,0.00008377186,0.00004020921,0.00003654448,0.00004754804,0.00004586381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008230516,0.00001145548,0.0005297156,0.00006153405,0.00001303164,0.00004744261,0.00002579784,0.0002871763,0.9953116,0.0002326434,0.00006642342,0.003330821],"study_design_scores_gemma":[0.000009605942,0.00005758236,0.001947417,0.000004612851,0.00001242329,0.0002279571,0.00004391414,0.009854518,0.9851601,0.0001680828,0.002503979,0.000009718229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8406423,0.002081932,0.1520256,0.0002410285,0.00004976376,0.0001418932,0.001930001,0.001220455,0.001667042],"genre_scores_gemma":[0.8433704,0.001837821,0.148972,0.0001036932,0.000006965067,0.0001071297,0.002615023,0.0002009485,0.002786031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001374861,"threshold_uncertainty_score":0.004078448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005391968468450902,"score_gpt":0.2550105136522465,"score_spread":0.2496185451837956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}