{"id":"W2944717492","doi":"10.1158/1538-7445.sabcs18-ot1-06-01","title":"Abstract OT1-06-01: ANG1005 in leptomeningeal disease (ANGLeD) trial: A randomized, open-label, phase 3 study of ANG1005 compared with Physician's Best Choice in HER2-negative breast cancer patients with newly diagnosed leptomeningeal carcinomatosis and previously treated brain metastases","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Angiochem (Canada)","funders":"","keywords":"Medicine; Breast cancer; Internal medicine; Capecitabine; Metastatic breast cancer; Cancer; Oncology; Eribulin; Chemotherapy; Phases of clinical research; Gastroenterology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001163835,0.001586692,0.002044308,0.0003706303,0.0004204067,0.001021181,0.0008325978,0.001595868,0.007149657],"category_scores_gemma":[0.0009957678,0.0004957271,0.001262995,0.0003181518,0.001117636,0.0008972641,0.0003695001,0.003016987,0.001107695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006144321,"about_ca_system_score_gemma":0.0009730231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001046669,"about_ca_topic_score_gemma":0.002555137,"domain_scores_codex":[0.9996663,0.0001536463,0.00001465857,0.00005640701,0.00002819056,0.00008067851],"domain_scores_gemma":[0.9992529,0.0001521251,0.000161352,0.00003798215,0.00003249173,0.0003631052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.970525,0.01272196,0.001078708,0.0003182647,0.0004003824,0.00005380299,0.00003966665,0.0002804576,0.003219255,0.0001058075,0.0009859448,0.01027071],"study_design_scores_gemma":[0.8920767,0.1043034,0.002188198,0.00001527427,0.000181419,0.00003218665,0.00001636594,0.0003721978,0.0003260511,0.00008792971,0.0003888933,0.00001141713],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921734,0.001262175,0.0002413179,0.0004390361,0.0002493308,0.002933313,0.0009558965,0.00008658239,0.001658955],"genre_scores_gemma":[0.9869112,0.001211537,0.001181994,0.001374899,0.0003746837,0.003764554,0.001524718,0.00002043,0.003635887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007149657,"threshold_uncertainty_score":0.02391803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05972211473529758,"score_gpt":0.4029597303643158,"score_spread":0.3432376156290182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}