{"id":"W2944756121","doi":"10.1007/s40265-019-01115-y","title":"Dacomitinib in the Management of Advanced Non-Small-Cell Lung Cancer","year":2019,"lang":"en","type":"review","venue":"Drugs","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Pfizer","keywords":"Erlotinib; Medicine; Gefitinib; Lung cancer; Tyrosine-kinase inhibitor; Epidermal growth factor receptor; Oncology; Pharmacology; Cancer; Erlotinib Hydrochloride; EGFR inhibitors; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004771916,0.0006313809,0.001442795,0.001633333,0.0001978595,0.0009113442,0.0006685864,0.0007593535,0.003578867],"category_scores_gemma":[0.0008051007,0.0001860047,0.0005734841,0.001589766,0.0002798159,0.0007350045,0.0004552089,0.001749507,0.001021543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006067095,"about_ca_system_score_gemma":0.000814896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00146204,"about_ca_topic_score_gemma":0.004701281,"domain_scores_codex":[0.9998429,0.000029632,0.00002466641,0.00002781708,0.00005770702,0.00001731466],"domain_scores_gemma":[0.999694,0.0001739921,0.00005202011,0.000005013808,0.00005144579,0.0000234105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001153354,0.00004161231,0.0001042838,0.01707864,0.0001574367,0.00007852082,0.00002064029,0.0003298126,0.0006523691,0.00169732,0.02815105,0.951573],"study_design_scores_gemma":[0.0001083653,0.0001772172,0.001087044,0.009421316,0.0005314446,0.000939992,0.00003997342,0.0001937387,0.0003167502,0.001653186,0.9855079,0.00002310895],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006431329,0.9990369,0.00003714954,0.0001707871,0.0001120876,0.000002595003,0.00001842345,0.000003705268,0.0005540201],"genre_scores_gemma":[0.0005889409,0.9985973,0.00008394688,0.0002460219,0.0001042962,0.000003900091,0.00002629517,8.253301e-7,0.0003483137],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003578867,"threshold_uncertainty_score":0.01197255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0261137380604118,"score_gpt":0.3865650029237402,"score_spread":0.3604512648633285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}