{"id":"W2944808953","doi":"10.1158/1538-7445.am10-sy31-04","title":"Abstract SY31-04: Metabolic regulation of tumor cells survival","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Warburg effect; Glycolysis; Anaerobic glycolysis; Cancer cell; Cancer; Oxidative phosphorylation; Cancer research; Angiogenesis; Cell biology; Cell; Programmed cell death; Cell growth; Metabolic pathway; Biology; Downregulation and upregulation; Metabolism; Biochemistry; Chemistry; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001255429,0.0004606836,0.0002586068,0.000489477,0.0003131068,0.0006053647,0.000316274,0.0004384097,0.0126932],"category_scores_gemma":[0.00008018804,0.0001466974,0.000168096,0.0003505749,0.0002272966,0.0002868005,0.0002945095,0.0005558668,0.003093247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00085998,"about_ca_system_score_gemma":0.0005259183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001244447,"about_ca_topic_score_gemma":0.001649163,"domain_scores_codex":[0.9999286,0.00001013148,0.00000357266,0.00001654534,0.00002615269,0.00001501118],"domain_scores_gemma":[0.9999593,0.000004381154,0.000007435031,0.000002615009,0.00001332273,0.00001291688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003199303,0.0002983798,0.001241062,0.00122929,0.00003588503,0.0008079406,0.00005230312,0.001689056,0.7273839,0.006893581,0.05505724,0.2021122],"study_design_scores_gemma":[0.0003980087,0.001563017,0.03110606,0.0002061407,0.00006839656,0.002044454,0.0001099958,0.004343054,0.6825212,0.002929058,0.2746717,0.00003895138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5277302,0.2472409,0.008144302,0.01794523,0.005779263,0.0004001076,0.008157261,0.001173482,0.1834292],"genre_scores_gemma":[0.7227693,0.07812882,0.00370915,0.001029607,0.001000055,0.0001259154,0.007017125,0.00008628506,0.1861337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0126932,"threshold_uncertainty_score":0.04246294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03601683364735442,"score_gpt":0.3575787730086165,"score_spread":0.3215619393612621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}