{"id":"W2945006162","doi":"10.1016/j.yjmcc.2019.05.014","title":"Transcript levels for extracellular matrix proteins are altered in MK5-deficient cardiac ventricular fibroblasts","year":2019,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Fondation Institut de Cardiologie de Montréal; Université de Montréal; Heart and Stroke Foundation of Canada","keywords":"Extracellular matrix; Myofibroblast; Messenger RNA; Fibroblast; Endocrinology; Internal medicine; Type I collagen; Cell biology; Biology; Chemistry; Medicine; Fibrosis; Cell culture; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009778272,0.0002656479,0.001372459,0.0003161951,0.00004363467,0.00002548701,0.0001085806,0.0002906839,0.00001111379],"category_scores_gemma":[0.00005701809,0.000217363,0.001248986,0.0001741376,0.00005611144,0.00006376685,0.00003599111,0.0004164811,0.000004604152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000924296,"about_ca_system_score_gemma":0.0001233534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005398455,"about_ca_topic_score_gemma":2.950561e-7,"domain_scores_codex":[0.9978648,0.0002118857,0.0007611183,0.0003566464,0.0003610012,0.0004444973],"domain_scores_gemma":[0.9988767,0.0000495504,0.000315206,0.0003092462,0.0002506664,0.0001986579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004433814,0.00006552923,0.007702196,0.0003872765,0.000393063,0.0006346836,0.000120614,0.005162943,0.9843199,0.0001747017,0.0000943401,0.0005013415],"study_design_scores_gemma":[0.03288461,0.008422877,0.05357542,0.003575138,0.004221248,0.01011467,0.003231401,0.008118967,0.7945465,0.001122576,0.07791086,0.002275702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.91478,0.05027566,0.03273568,0.0002987574,0.0007253712,0.001060862,0.00002664759,0.000008868818,0.00008817087],"genre_scores_gemma":[0.9973692,0.0001928377,0.001812638,0.00005033815,0.00034408,0.00001502505,0.00001521754,0.00004599455,0.0001546286],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1897734,"threshold_uncertainty_score":0.8863804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353948255463664,"score_gpt":0.2473291711140493,"score_spread":0.2337896885594126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}