{"id":"W2945009381","doi":"10.1002/advs.201900712","title":"Prediction of DNA Integrity from Morphological Parameters Using a Single‐Sperm DNA Fragmentation Index Assay","year":2019,"lang":"en","type":"article","venue":"Advanced Science","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; Ottawa Fertility Centre; University of Toronto; University of New Brunswick","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto; California HIV/AIDS Research Program","keywords":"Sperm; DNA fragmentation; Acridine orange; Biology; Logistic regression; Andrology; Linear regression; Biological system; Statistics; Mathematics; Genetics; Medicine; Staining","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003937688,0.0006386486,0.0007221051,0.003127361,0.0001868444,0.0009876037,0.0005593592,0.0006664383,0.001126663],"category_scores_gemma":[0.0109115,0.0002305401,0.0006443899,0.00209285,0.0003973462,0.0005286341,0.0004592744,0.0006465405,0.0006323245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000312078,"about_ca_system_score_gemma":0.0003356922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008859172,"about_ca_topic_score_gemma":0.001324803,"domain_scores_codex":[0.997761,0.000605639,0.0002083006,0.0005171472,0.0008482406,0.00005957379],"domain_scores_gemma":[0.989242,0.00540745,0.002273057,0.0007402169,0.002166803,0.0001705393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008492388,0.0002362347,0.7699945,0.001028491,0.001450237,0.0001425092,0.0002301514,0.005107732,0.03478119,0.0003003762,0.0009034161,0.1849759],"study_design_scores_gemma":[0.0000321897,0.002298715,0.872256,0.0004299761,0.00133763,0.001709966,0.0002822187,0.03584823,0.07800733,0.000888796,0.006758258,0.0001507169],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8822942,0.02821254,0.08114333,0.0002210999,0.0000971228,0.0003163216,0.004033098,0.0004399903,0.003242335],"genre_scores_gemma":[0.9774036,0.004387819,0.01539264,0.00007673381,0.00003621566,0.0001041165,0.001600343,0.00003423348,0.0009641457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003937688,"threshold_uncertainty_score":0.02082473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05115099689517185,"score_gpt":0.2920945420055887,"score_spread":0.2409435451104169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}