{"id":"W2945082608","doi":"10.1016/j.jgar.2019.05.005","title":"Efficacy of newly isolated and highly potent bacteriophages in a mouse model of extensively drug-resistant Acinetobacter baumannii bacteraemia","year":2019,"lang":"en","type":"article","venue":"Journal of Global Antimicrobial Resistance","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Acinetobacter baumannii; Galleria mellonella; Imipenem; Microbiology; Phage therapy; Drug resistance; Bacteremia; Lytic cycle; Septic shock; Medicine; Bacteriophage; Biology; Virology; Antibiotics; Antibiotic resistance; Bacteria; Escherichia coli; Immunology; Virulence; Sepsis; Virus; Pseudomonas aeruginosa","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005530498,0.001115654,0.0007005756,0.0006757228,0.0002138162,0.0004036803,0.00044264,0.000880082,0.001167381],"category_scores_gemma":[0.0001791817,0.0002958578,0.0005338315,0.000247518,0.0005176796,0.0004917795,0.0002321733,0.001688185,0.0003335909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003634099,"about_ca_system_score_gemma":0.0003088011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004654411,"about_ca_topic_score_gemma":0.0007022547,"domain_scores_codex":[0.9995702,0.00008083092,0.00003712605,0.00008488331,0.0001026811,0.0001241856],"domain_scores_gemma":[0.9996431,0.00004910203,0.0001114536,0.00003086059,0.00002775439,0.0001377751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001364028,0.0009200908,0.0001498363,0.000121566,0.00001384531,0.00004952479,0.00003709688,0.0001335152,0.9948949,0.0000680407,0.00008612814,0.002161357],"study_design_scores_gemma":[0.0004708967,0.03370568,0.00485268,0.00005168575,0.000074485,0.0002358824,0.0000751252,0.001250193,0.9572114,0.00006754156,0.001983446,0.00002104443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950052,0.001979263,0.001167387,0.0001742261,0.0001001254,0.0001171514,0.0004194344,0.0001475294,0.0008897185],"genre_scores_gemma":[0.9882736,0.002396304,0.002931459,0.0001408042,0.00006098711,0.000348435,0.0007976567,0.00003266435,0.005018048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001167381,"threshold_uncertainty_score":0.003905296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005888484892047239,"score_gpt":0.2193328264272572,"score_spread":0.21344434153521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}