{"id":"W2945149499","doi":"10.2147/ceg.s186958","title":"<p>Combined EsophaCap cytology and MUC2 immunohistochemistry for screening of intestinal metaplasia, dysplasia and carcinoma</p>","year":2019,"lang":"en","type":"article","venue":"Clinical and Experimental Gastroenterology","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Ontario Institute for Cancer Research","funders":"National Cancer Institute; University of Rochester","keywords":"Medicine; Dysplasia; Cytology; Intestinal metaplasia; Adenocarcinoma; Cytopathology; Esophagus; Barrett's esophagus; Biopsy; Gastroenterology; Gold standard (test); Pathology; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001493676,0.0006123947,0.0003403656,0.002235558,0.00035928,0.0006154792,0.000507858,0.0004392457,0.001599441],"category_scores_gemma":[0.002552605,0.0002474911,0.0003760965,0.0007913781,0.0007555252,0.0004912927,0.0005302429,0.0002473182,0.0006456606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007020794,"about_ca_system_score_gemma":0.0008390549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006060126,"about_ca_topic_score_gemma":0.01353433,"domain_scores_codex":[0.998928,0.0002007249,0.0001445293,0.0001804173,0.0004514558,0.00009481753],"domain_scores_gemma":[0.9986059,0.0002700896,0.0002993848,0.0001334542,0.0005150001,0.0001761457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007681997,0.00005142631,0.9250781,0.0001948624,0.0001318095,0.002139857,0.00009382721,0.0002788646,0.04375058,0.00004069767,0.0004442778,0.02702738],"study_design_scores_gemma":[0.00004505971,0.000773932,0.9152025,0.0001426688,0.0002688642,0.01996916,0.000294365,0.004777161,0.056043,0.00007445893,0.002383949,0.00002488042],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863099,0.003525311,0.005160363,0.0001260988,0.00003564493,0.000193624,0.0004447671,0.000168839,0.004035532],"genre_scores_gemma":[0.9924487,0.0004942199,0.006136245,0.0000620422,0.00001736114,0.00003758792,0.0002636521,0.0000166542,0.0005234819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006060126,"threshold_uncertainty_score":0.01204967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02623394997607149,"score_gpt":0.345433523922299,"score_spread":0.3191995739462275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}