{"id":"W2945159822","doi":"10.1371/journal.pgen.1008150","title":"Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans","year":2019,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institutes of Health; National Research Foundation of Korea","keywords":"Biology; Autophagy; DNA damage; Cell biology; Germ cell; Germline; Apoptosis; Programmed cell death; Granule (geology); Cytoplasm; Mutant; Somatic cell; DNA; Molecular biology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009756736,0.0004980428,0.0003618449,0.0003013619,0.0002624645,0.0004126333,0.0002532114,0.0003819852,0.0005370552],"category_scores_gemma":[0.0001281787,0.0002426056,0.0005376462,0.0001160376,0.0003672708,0.0002857993,0.0004369846,0.0007718296,0.000265223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005654813,"about_ca_system_score_gemma":0.0004305396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001232781,"about_ca_topic_score_gemma":0.001814244,"domain_scores_codex":[0.9998719,0.000008141184,0.00001547063,0.00003121835,0.00004098377,0.00003226897],"domain_scores_gemma":[0.9997849,0.00002454814,0.00007839546,0.00002039953,0.00001584148,0.00007592959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007464505,0.00001228737,0.0002304509,0.00002724856,0.000002666047,0.00005594726,0.000008950246,0.00004829745,0.999193,0.00003493176,0.00001747913,0.0002939918],"study_design_scores_gemma":[0.00002153579,0.000109099,0.0227692,0.00001593435,0.00002401492,0.0003419339,0.00004618741,0.001599918,0.9733925,0.00007871998,0.001589334,0.00001157257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969996,0.0007896695,0.001264672,0.00006796449,0.00001601092,0.00001604376,0.0002866167,0.00008793439,0.0004714727],"genre_scores_gemma":[0.9963721,0.0004132687,0.001227659,0.00005679376,0.000004703797,0.00003189422,0.0006397502,0.00004464243,0.001209112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001232781,"threshold_uncertainty_score":0.004102886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01049823779900537,"score_gpt":0.215211406781231,"score_spread":0.2047131689822256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}