{"id":"W2945198568","doi":"10.1007/s12195-019-00574-3","title":"Type I Diabetes Delays Perfusion and Engraftment of 3D Constructs by Impinging on Angiogenesis; Which can be Rescued by Hepatocyte Growth Factor Supplementation","year":2019,"lang":"en","type":"article","venue":"Cellular and Molecular Bioengineering","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Heart and Stroke Foundation; Toronto General Hospital; University of Toronto; University Health Network","funders":"National Institute of Biomedical Imaging and Bioengineering; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Canada First Research Excellence Fund; Heart and Stroke Foundation of Canada; Institute of Circulatory and Respiratory Health; University of Toronto; American Heart Association","keywords":"Hepatocyte growth factor; Angiogenesis; Microvessel; Sprouting angiogenesis; Vascular endothelial growth factor; Blood vessel; Growth factor; Neovascularization; In vivo; Cell biology; Medicine; Pathology; Cancer research; Biology; Immunology; Receptor; Endocrinology; Internal medicine; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002273044,0.0004794603,0.0003191823,0.0002358399,0.0001765131,0.0005681168,0.0002324609,0.000394206,0.001831432],"category_scores_gemma":[0.0001122508,0.0002673393,0.0003979696,0.0001897042,0.0003266886,0.0003472326,0.0002776244,0.001287865,0.000358812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003342305,"about_ca_system_score_gemma":0.0003620259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001488238,"about_ca_topic_score_gemma":0.002407593,"domain_scores_codex":[0.99981,0.00002190225,0.00001688531,0.00004103423,0.000052443,0.00005772367],"domain_scores_gemma":[0.9997765,0.00004904717,0.00006789035,0.00002851238,0.00001522126,0.00006269617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001084481,0.00002982241,0.00009410129,0.00002363901,0.000004759305,0.00003900369,0.00002794898,0.00008546378,0.9984757,0.0002086144,0.00005431745,0.0008481673],"study_design_scores_gemma":[0.00001077084,0.0001007226,0.00151349,0.000006538624,0.00001352053,0.00008637337,0.00002891008,0.0005653211,0.9953611,0.00003739016,0.002272408,0.000003440182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854895,0.001109777,0.008921227,0.0001962861,0.0001246018,0.00002721069,0.0004432898,0.0001812751,0.003506737],"genre_scores_gemma":[0.985023,0.0008062398,0.006650562,0.0000928329,0.00001480342,0.00004307659,0.0006653379,0.000105911,0.006598392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001831432,"threshold_uncertainty_score":0.006126761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00549937818666429,"score_gpt":0.2008742060525286,"score_spread":0.1953748278658643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}