{"id":"W2945198568","doi":"10.1007/s12195-019-00574-3","title":"Type I Diabetes Delays Perfusion and Engraftment of 3D Constructs by Impinging on Angiogenesis; Which can be Rescued by Hepatocyte Growth Factor Supplementation","year":2019,"lang":"en","type":"article","venue":"Cellular and Molecular Bioengineering","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Heart and Stroke Foundation; Toronto General Hospital; University of Toronto; University Health Network","funders":"National Institute of Biomedical Imaging and Bioengineering; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Canada First Research Excellence Fund; Heart and Stroke Foundation of Canada; Institute of Circulatory and Respiratory Health; University of Toronto; American Heart Association","keywords":"Hepatocyte growth factor; Angiogenesis; Microvessel; Sprouting angiogenesis; Vascular endothelial growth factor; Blood vessel; Growth factor; Neovascularization; In vivo; Cell biology; Medicine; Pathology; Cancer research; Biology; Immunology; Receptor; Endocrinology; Internal medicine; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007077707,0.000169595,0.0002474366,0.0001115486,0.00003465419,0.00001612052,0.00002697508,0.00006826894,0.00004143419],"category_scores_gemma":[0.0000385981,0.0001586739,0.000034646,0.0001444049,0.00002297085,0.00002818892,0.0000280417,0.00006393484,0.000001189411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003246882,"about_ca_system_score_gemma":0.00002142891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003090778,"about_ca_topic_score_gemma":3.96078e-7,"domain_scores_codex":[0.9991951,0.00001954241,0.0001765611,0.000237017,0.000164454,0.000207343],"domain_scores_gemma":[0.9995952,0.00002959166,0.00004435002,0.0001355982,0.00006897817,0.0001262806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003045589,0.0000216728,0.01572706,0.0001998905,0.0000703713,0.000002506972,0.0001049426,0.00001177624,0.983202,0.00005691878,0.00009442346,0.0004780249],"study_design_scores_gemma":[0.00124527,0.000408348,0.0007442854,0.0001192519,0.00008829118,0.000002742615,0.00009310702,0.004000291,0.9927321,0.000002363009,0.0004106316,0.0001533144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958628,0.00296883,0.0004427199,0.0001231098,0.00008561309,0.0003290591,0.00005860659,0.00003182834,0.0000974258],"genre_scores_gemma":[0.9985981,0.0002931956,0.0005455314,0.0001555349,0.00001111119,0.000007733785,0.0003237728,0.00002580417,0.00003922652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01498277,"threshold_uncertainty_score":0.6470532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00549937818666429,"score_gpt":0.2008742060525286,"score_spread":0.1953748278658643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}