{"id":"W2945224060","doi":"10.1099/jmm.0.001001","title":"Sequence similarity searches for morphine biosynthesis enzymes in bacteria yield putative targets for understanding associations between infection and opiate administration","year":2019,"lang":"en","type":"article","venue":"Journal of Medical Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health; University of British Columbia","funders":"","keywords":"Pseudomonas aeruginosa; Acinetobacter baumannii; Microbiology; Enterococcus faecalis; Klebsiella pneumoniae; Biology; Klebsiella oxytoca; Demethylase; Enterobacter; Drug resistance; Bacteria; Staphylococcus aureus; Escherichia coli; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002577917,0.0003533257,0.0004064635,0.000998023,0.0003371898,0.0003849605,0.0001729628,0.0003129674,0.002342473],"category_scores_gemma":[0.0007500226,0.0001107264,0.0004743681,0.001181917,0.0001392932,0.0002553741,0.0002755244,0.0003629603,0.0008316237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002303729,"about_ca_system_score_gemma":0.0003354945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007064066,"about_ca_topic_score_gemma":0.001444164,"domain_scores_codex":[0.999793,0.00004698509,0.00002703551,0.0000432238,0.00005178445,0.00003800667],"domain_scores_gemma":[0.9995643,0.000121077,0.0001494662,0.00002859425,0.00006482261,0.00007176359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006482811,0.0001263001,0.0273738,0.0004035583,0.00007734691,0.0006856063,0.0001762396,0.0003529738,0.9559199,0.0002509386,0.0002373015,0.01374768],"study_design_scores_gemma":[0.0000695741,0.001848324,0.5562931,0.0001541567,0.0003688963,0.005811424,0.001209276,0.009250388,0.4021567,0.0009269233,0.02185196,0.00005924775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853215,0.002512147,0.005925297,0.000142905,0.00002318625,0.00009266005,0.003627219,0.0001275942,0.002227596],"genre_scores_gemma":[0.9718891,0.0009936503,0.01786949,0.00008494332,0.00001745514,0.0000559758,0.007852381,0.00003097788,0.001205913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002342473,"threshold_uncertainty_score":0.007836342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09374558918292573,"score_gpt":0.3590702858856537,"score_spread":0.265324696702728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}