{"id":"W2945234740","doi":"10.1101/640300","title":"CELF1 is an EIF4E binding protein that promotes translation of epithelial-mesenchymal transition effector mRNAs","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Cancer Institute; Cancer Prevention and Research Institute of Texas; American Cancer Society","keywords":"EIF4E; EIF4G; Initiation factor; Cell biology; Eukaryotic translation; Eukaryotic initiation factor; Messenger RNA; Translation (biology); RNA-binding protein; Biology; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001305335,0.0002563247,0.0001803746,0.0002631259,0.000287741,0.0002683621,0.0001552385,0.0003227028,0.002541777],"category_scores_gemma":[0.0001285765,0.0001207919,0.0001898334,0.0001237642,0.0002161431,0.00009919301,0.0001926269,0.000420132,0.001150039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003658379,"about_ca_system_score_gemma":0.0001838985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006134417,"about_ca_topic_score_gemma":0.0007580774,"domain_scores_codex":[0.9999123,0.00000952742,0.000003383268,0.00002023529,0.00002787587,0.0000267092],"domain_scores_gemma":[0.9999559,0.000008948866,0.000007714618,0.00000351668,0.00000633671,0.00001752285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001006526,0.00002540266,0.0003388732,0.00004278533,0.000003850268,0.0001279841,0.000007703957,0.00007148752,0.9969553,0.0002473729,0.0003146468,0.001764002],"study_design_scores_gemma":[0.00001803348,0.00006082516,0.00609992,0.00000609233,0.000004213663,0.0004419834,0.00002028094,0.00125516,0.9830405,0.0001367301,0.008912672,0.000003580864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9590367,0.006614885,0.01802815,0.0009020762,0.0003723102,0.00005770603,0.001616685,0.000625291,0.0127461],"genre_scores_gemma":[0.9741245,0.00111653,0.007286578,0.0001577774,0.00005288217,0.00003184212,0.002071014,0.00006520668,0.01509379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002541777,"threshold_uncertainty_score":0.008503079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01754029486137198,"score_gpt":0.2236861269253994,"score_spread":0.2061458320640275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}