{"id":"W2945416434","doi":"10.1016/j.omto.2019.05.001","title":"An Oncolytic Adenovirus Vector Expressing p14 FAST Protein Induces Widespread Syncytium Formation and Reduces Tumor Growth Rate In Vivo","year":2019,"lang":"en","type":"article","venue":"Molecular Therapy — Oncolytics","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Oncolytic virus; In vivo; Cancer research; Oncolytic adenovirus; Virotherapy; Viral vector; Biology; Cancer; Cell; Cell growth; Cancer cell; Lung cancer; Medicine; Tumor cells; Pathology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007748132,0.0004195367,0.0003911245,0.0002340979,0.0001216135,0.0002167315,0.0005044642,0.0002659052,0.00004999171],"category_scores_gemma":[0.00008183425,0.0004136568,0.00009909263,0.0003349053,0.0001458944,0.00006903732,0.0001141665,0.0003262692,0.00002245819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001425999,"about_ca_system_score_gemma":0.000347768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004633207,"about_ca_topic_score_gemma":0.00007048739,"domain_scores_codex":[0.997199,0.000523761,0.0004901549,0.0007321191,0.0004252354,0.0006297289],"domain_scores_gemma":[0.9986535,0.00003602258,0.0002269513,0.0006952246,0.0001763101,0.0002119895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002013212,0.0002363953,0.0002166259,0.00006003373,0.00005595604,0.00004126046,0.0003435462,0.0001976598,0.9913986,0.00003302707,0.00003142565,0.005372216],"study_design_scores_gemma":[0.002522854,0.004571707,0.0002537521,0.0001444643,0.00001002382,0.00001974921,0.0002531618,0.0009866015,0.9898434,0.0001556008,0.000737206,0.000501483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956528,0.001614783,0.0003685876,0.0001910815,0.0001126697,0.001611635,0.00002409883,0.00004100792,0.0003833521],"genre_scores_gemma":[0.9980534,0.0002606998,0.0004647303,0.000529931,0.0001383055,0.0001799243,0.00004901545,0.0001091774,0.0002148523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004870732,"threshold_uncertainty_score":0.9998315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01492142282913653,"score_gpt":0.2870929348740132,"score_spread":0.2721715120448767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}