{"id":"W2945506136","doi":"10.1083/jcb.201810118","title":"Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies","year":2019,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Consejo Superior de Investigaciones Científicas; British Heart Foundation; McGill University","keywords":"Microtubule; Cell biology; GTPase; Histamine; Rab; Dynein; Stimulation; Organelle; Intracellular; Biology; Chemistry; Neuroscience; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001012854,0.0001705318,0.0001363963,0.0001276782,0.0001572184,0.0003380742,0.0001033796,0.0002736403,0.001146464],"category_scores_gemma":[0.00008666494,0.00008866346,0.0001961924,0.00007157159,0.0001421198,0.0003218597,0.000202705,0.0002972724,0.0004461814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002049262,"about_ca_system_score_gemma":0.0001105388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003070825,"about_ca_topic_score_gemma":0.0005717183,"domain_scores_codex":[0.9998764,0.00002228561,0.000007447471,0.00002672228,0.00001868787,0.00004848675],"domain_scores_gemma":[0.9999543,0.000004741694,0.00001090811,0.000006757223,0.00000708788,0.00001620292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001454416,0.00001036016,0.0002878284,0.00002071985,0.00000315219,0.0001046432,0.00001414782,0.0000522988,0.9977735,0.0002154675,0.00005145632,0.001320972],"study_design_scores_gemma":[0.00003453813,0.0001663487,0.01490049,0.000006348916,0.00001415764,0.0005508438,0.0000935503,0.002932361,0.9778665,0.0001396839,0.003286564,0.000008740139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938646,0.001823015,0.002341513,0.0001503642,0.0000342053,0.0000131353,0.0001234392,0.00007309618,0.001576633],"genre_scores_gemma":[0.9972356,0.0004372662,0.0006225486,0.00002631607,0.000007424785,0.000005941159,0.00006306073,0.000007947618,0.001594056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001146464,"threshold_uncertainty_score":0.00383532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006959584135219556,"score_gpt":0.2339655748550609,"score_spread":0.2270059907198413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}