{"id":"W2945538939","doi":"10.1016/j.chembiol.2019.03.018","title":"Vaccination with Tumor-Ganglioside Glycomimetics Activates a Selective Immunity that Affords Cancer Therapy","year":2019,"lang":"en","type":"article","venue":"Cell chemical biology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Glycomics Network; Canadian Institutes of Health Research","keywords":"Vaccination; Ganglioside; Medicine; Immunity; Cancer; Cancer therapy; Immunology; Immune system; Chemistry; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001019137,0.0004107657,0.0002553935,0.0002413688,0.0001029099,0.0002056755,0.0001436194,0.0003107971,0.001281199],"category_scores_gemma":[0.00009609132,0.0001285514,0.0001885569,0.0001054245,0.0001791622,0.0001654094,0.0002187656,0.0007404869,0.0004137588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002331583,"about_ca_system_score_gemma":0.0002175415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002714751,"about_ca_topic_score_gemma":0.0004671387,"domain_scores_codex":[0.9999098,0.00001237953,0.000004571975,0.00001548028,0.00002468966,0.00003321787],"domain_scores_gemma":[0.9999586,0.000008726921,0.000009966771,0.000005121127,0.000004307752,0.00001315606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001307963,0.00004948367,0.00007925754,0.0000177572,0.000003598131,0.00002161112,0.000006188944,0.0001398654,0.9971043,0.0001993205,0.00006576681,0.002182041],"study_design_scores_gemma":[0.00006472777,0.0007911942,0.001127691,0.000004029645,0.00001712046,0.0001703807,0.000009726872,0.001112446,0.9943444,0.0001339697,0.002221252,0.000003213497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875094,0.001333821,0.005553275,0.0002774939,0.0001113553,0.0001327165,0.0002937566,0.0002503472,0.004537751],"genre_scores_gemma":[0.9956994,0.0005740147,0.00177325,0.0000735693,0.0000246063,0.00003607044,0.0001790965,0.00001725145,0.001622865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001281199,"threshold_uncertainty_score":0.004286051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01192105576461027,"score_gpt":0.2729213951870896,"score_spread":0.2610003394224794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}