{"id":"W2945538939","doi":"10.1016/j.chembiol.2019.03.018","title":"Vaccination with Tumor-Ganglioside Glycomimetics Activates a Selective Immunity that Affords Cancer Therapy","year":2019,"lang":"en","type":"article","venue":"Cell chemical biology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Glycomics Network; Canadian Institutes of Health Research","keywords":"Vaccination; Ganglioside; Medicine; Immunity; Cancer; Cancer therapy; Immunology; Immune system; Chemistry; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001209633,0.0001935011,0.0001945283,0.00005769151,0.00005738132,0.00001869498,0.0002499817,0.0002228312,0.0003393712],"category_scores_gemma":[0.00003877713,0.0001466734,0.00006657906,0.0001751144,0.00007513302,0.000006257929,0.0001095737,0.0002483418,0.00003501176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004642252,"about_ca_system_score_gemma":0.0001197306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009141838,"about_ca_topic_score_gemma":0.00001720836,"domain_scores_codex":[0.9989359,0.00007542144,0.0001301415,0.0003974874,0.0001111027,0.000349917],"domain_scores_gemma":[0.9992775,0.00004318445,0.00008992389,0.0003237882,0.0001794027,0.00008622697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006945402,0.00009678792,0.02116837,0.00001515052,0.00005178265,0.000001020834,0.00003360036,0.000007721334,0.9758929,0.00003843763,0.0002636666,0.001736034],"study_design_scores_gemma":[0.001450384,0.0005298425,0.0022325,0.000006113246,0.000005737927,0.000008467096,0.00004944528,0.00005623919,0.9875427,0.0001389364,0.007768153,0.0002114721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943851,0.0007316261,0.0001314891,0.0001666193,0.00006105452,0.0004335571,0.00001662579,0.00002167809,0.004052287],"genre_scores_gemma":[0.998243,0.0002407753,0.0002339104,0.0002941733,0.00009193089,0.00008271259,0.0001716606,0.0000266128,0.0006151888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01893587,"threshold_uncertainty_score":0.5981168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01192105576461027,"score_gpt":0.2729213951870896,"score_spread":0.2610003394224794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}