{"id":"W2945664876","doi":"10.1093/annonc/mdz152","title":"Journey’s end: the quest for BRCA-like hereditary breast cancer genes is nearly over","year":2019,"lang":"en","type":"letter","venue":"Annals of Oncology","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Cancer; Breast cancer; Gene; Oncology; Genetics; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003507253,0.0009328462,0.001664164,0.0008658445,0.005578238,0.004813049,0.001401966,0.0550952,0.008305623],"category_scores_gemma":[0.01949244,0.0008621513,0.001135628,0.0006496072,0.004047622,0.006307281,0.002585643,0.04885592,0.005012766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003662048,"about_ca_system_score_gemma":0.004894443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004281612,"about_ca_topic_score_gemma":0.009019841,"domain_scores_codex":[0.9969626,0.0009681607,0.0002681857,0.0003307277,0.0009786434,0.0004916256],"domain_scores_gemma":[0.9920198,0.003731131,0.0004174152,0.0002890193,0.0009890491,0.002553606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005345963,0.00006062589,0.0004599851,0.00004575344,0.00001559208,0.001789048,0.0001182452,0.00003721883,0.0001565524,0.002758593,0.9864262,0.008078568],"study_design_scores_gemma":[0.000131647,0.00009211298,0.001085746,0.000333846,0.00003097994,0.003106232,0.0005509108,0.0002769551,0.0001164052,0.01544857,0.9787589,0.00006762191],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001877995,0.002206228,0.00003837114,0.9784514,0.01756701,0.000003871477,0.00001151273,0.00001196621,0.001521761],"genre_scores_gemma":[0.00233693,0.002308955,0.0001291762,0.917088,0.07262078,0.00001396194,0.00001467471,0.00001555778,0.005471977],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0550952,"threshold_uncertainty_score":0.027785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0499130223931575,"score_gpt":0.3677638843109602,"score_spread":0.3178508619178027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}