{"id":"W2945709402","doi":"10.1016/j.neuron.2019.04.029","title":"A Fear Memory Engram and Its Plasticity in the Hypothalamic Oxytocin System","year":2019,"lang":"en","type":"article","venue":"Neuron","topic":"Neuroendocrine regulation and behavior","field":"Psychology","cited_by":143,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"FP7 Health; Campus France; Max-Planck-Gesellschaft; Université de Strasbourg; Centre National de la Recherche Scientifique; Fritz Thyssen Stiftung; Fondation Fyssen; Agence Nationale de la Recherche; Deutscher Akademischer Austauschdienst; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Pacific Institute for Climate Solutions; Deutsche Forschungsgemeinschaft; National Alliance for Research on Schizophrenia and Depression; Human Frontier Science Program","keywords":"Optogenetics; Neuroscience; Amygdala; Fear conditioning; Oxytocin; Fear processing in the brain; Extinction (optical mineralogy); Freezing behavior; Psychology; Context (archaeology); Oxytocin receptor; Engram; Stimulation; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005613403,0.00009585894,0.000118318,0.0000632392,0.00002997765,0.00002045361,0.000119856,0.00002947112,0.0001519661],"category_scores_gemma":[0.00001265275,0.00007028735,0.00002736123,0.000102737,0.00001465433,0.0000381496,0.00002580881,0.0001927963,0.0004946634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001262225,"about_ca_system_score_gemma":0.000006487108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001747681,"about_ca_topic_score_gemma":0.00001017279,"domain_scores_codex":[0.9990901,0.0002288326,0.0001360604,0.0002378762,0.0001243416,0.0001828157],"domain_scores_gemma":[0.9995849,0.0001524788,0.00004179917,0.0001824012,0.00001037925,0.00002806438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00119356,0.002742479,0.3721214,0.001141899,0.00007728181,0.00424081,0.01119234,0.0002245905,0.4427865,0.09354705,0.02148961,0.04924244],"study_design_scores_gemma":[0.001272052,0.0002072042,0.990476,0.0000189663,0.00001790679,0.0004431181,0.0005296094,0.0004203558,0.001257927,0.000005943356,0.005234796,0.0001161555],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936347,0.00003141467,8.868122e-7,0.0005435045,0.0004696138,0.0004756666,0.000003668973,0.00005371783,0.004786824],"genre_scores_gemma":[0.996139,9.779172e-7,0.000002242651,0.0002454212,0.00004968655,0.00002818467,0.000001092653,0.00001437694,0.003519041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6183546,"threshold_uncertainty_score":0.6358062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02269282354991045,"score_gpt":0.2853046479269998,"score_spread":0.2626118243770893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}