{"id":"W2945725380","doi":"10.1113/jp277353","title":"High‐fat diet intake modulates maternal intestinal adaptations to pregnancy and results in placental hypoxia, as well as altered fetal gut barrier proteins and immune markers","year":2019,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Guelph","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Genome Canada","keywords":"Endocrinology; Internal medicine; Biology; Placenta; Offspring; Fetus; Inflammation; Gut flora; Barrier function; Hypoxia (environmental); Immune system; Pregnancy; Immunology; Medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001609502,0.0003234093,0.0002838436,0.0003702729,0.0001758899,0.0003208735,0.0002063953,0.0003224513,0.00167635],"category_scores_gemma":[0.000149439,0.0002774399,0.0002700932,0.0001929457,0.0003943992,0.0001888814,0.000324702,0.0008959771,0.0001726856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000419085,"about_ca_system_score_gemma":0.0002456337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009391475,"about_ca_topic_score_gemma":0.002427226,"domain_scores_codex":[0.9998042,0.00003021524,0.00001071821,0.00006414008,0.00003997616,0.00005081015],"domain_scores_gemma":[0.999814,0.0000184923,0.00007651478,0.00002134007,0.00001483318,0.0000548703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001973229,0.0001523694,0.004710281,0.00005219479,0.00002385451,0.0001023982,0.00006331002,0.00003981919,0.9898157,0.00008601848,0.00007686917,0.00290393],"study_design_scores_gemma":[0.0001503378,0.004783784,0.3664198,0.00007535335,0.0002551815,0.000955195,0.0005385361,0.001288443,0.6202893,0.0003027446,0.004904402,0.00003689729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973704,0.0006949313,0.0008416913,0.00009163999,0.00002007416,0.00001593546,0.0005394941,0.00002356897,0.000402233],"genre_scores_gemma":[0.991869,0.001024257,0.001767517,0.0001620166,0.0000124355,0.000104858,0.0006375146,0.00003381313,0.004388566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00167635,"threshold_uncertainty_score":0.005607963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00667527432984505,"score_gpt":0.2351925835470399,"score_spread":0.2285173092171949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}