{"id":"W2945746564","doi":"10.1161/circ.130.suppl_2.12519","title":"Abstract 12519: Regulation of Cardiac Fibroblast Phenotype by Scleraxis","year":2014,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Myofibroblast; Gene knockdown; Transactivation; Serum response factor; Cell biology; Cardiac fibrosis; Fibroblast; Biology; Transcription factor; Chromatin immunoprecipitation; Molecular biology; Gene expression; Fibrosis; Promoter; Medicine; Gene; Pathology; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001285795,0.0007960818,0.0003486104,0.0004445475,0.0002925377,0.0003967427,0.000439757,0.0004214134,0.0174955],"category_scores_gemma":[0.0001078339,0.0001700829,0.000376899,0.0004014895,0.0002008773,0.0001765942,0.0003308163,0.000710056,0.005823051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004060123,"about_ca_system_score_gemma":0.0003516115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009911002,"about_ca_topic_score_gemma":0.001026304,"domain_scores_codex":[0.9998226,0.00002039839,0.0000170578,0.00003398507,0.00007398597,0.00003203591],"domain_scores_gemma":[0.9999158,0.000009012415,0.00002140243,0.000005808452,0.00001359196,0.00003433374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003401792,0.00005974428,0.00007525574,0.000137463,0.000008564876,0.0001471003,0.000009788226,0.00003228296,0.9932671,0.0002078341,0.0009993102,0.004715431],"study_design_scores_gemma":[0.0002149177,0.0007496017,0.00818875,0.00003225068,0.00003580852,0.0008255234,0.00002634668,0.0004890409,0.9447472,0.0001196066,0.04455595,0.00001503544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8578417,0.02402531,0.02154062,0.002677314,0.001656465,0.0007345548,0.0279817,0.00209009,0.0614523],"genre_scores_gemma":[0.8247113,0.01080698,0.01281666,0.0008347347,0.0005621639,0.0006530476,0.0435059,0.0005252099,0.105584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0174955,"threshold_uncertainty_score":0.05852824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0125586573640568,"score_gpt":0.2362293286214465,"score_spread":0.2236706712573897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}