{"id":"W2945746564","doi":"10.1161/circ.130.suppl_2.12519","title":"Abstract 12519: Regulation of Cardiac Fibroblast Phenotype by Scleraxis","year":2014,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Myofibroblast; Gene knockdown; Transactivation; Serum response factor; Cell biology; Cardiac fibrosis; Fibroblast; Biology; Transcription factor; Chromatin immunoprecipitation; Molecular biology; Gene expression; Fibrosis; Promoter; Medicine; Gene; Pathology; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002227266,0.00008699132,0.0002373048,0.00006026597,0.00004553088,0.00001051947,0.00002310343,0.0001008719,0.00006487947],"category_scores_gemma":[0.00005696949,0.00008186447,0.0001573098,0.0001169672,0.00002736763,0.0000880172,0.000008945408,0.00006785665,0.00002461358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004549955,"about_ca_system_score_gemma":0.00002182666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004066715,"about_ca_topic_score_gemma":4.258256e-7,"domain_scores_codex":[0.9991966,0.00002313521,0.0002598223,0.0001724928,0.0002371963,0.000110758],"domain_scores_gemma":[0.9994227,0.00003806056,0.0001135839,0.0002347764,0.0001319617,0.00005887805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002848557,0.00002589687,0.02509095,0.0001162328,0.00002983315,1.717744e-8,0.00009152691,0.003214223,0.9432923,0.0002602927,0.0009420228,0.02690828],"study_design_scores_gemma":[0.0002942265,0.00002157661,0.967382,0.0001639318,0.00005105343,8.726739e-7,0.00001326934,0.01555121,0.01438486,0.0002078582,0.00184303,0.00008608214],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900184,0.000251368,0.003047113,0.0001138984,0.0001636073,0.0002036037,0.000008607189,0.0000433977,0.006150036],"genre_scores_gemma":[0.999024,0.00001259561,0.0004448098,0.0000277917,0.0002463728,0.000002426751,0.0001808753,0.00001865356,0.00004243384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9422911,"threshold_uncertainty_score":0.3338336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0125586573640568,"score_gpt":0.2362293286214465,"score_spread":0.2236706712573897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}