{"id":"W2945844299","doi":"10.1261/rna.069351.118","title":"HIV-1 requires Staufen1 to dissociate stress granules and to produce infectious viral particles","year":2019,"lang":"en","type":"article","venue":"RNA","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health; International AIDS Society","keywords":"Biology; Virology; Viral replication; Ribonucleoprotein; Translation (biology); HEK 293 cells; Viral entry; Capsid; RNA; Virus; Cell biology; Genetics; Gene; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001027817,0.0001038062,0.0001560515,0.00006102292,0.0001057908,0.0000271097,0.00008246641,0.00005398186,0.0001640539],"category_scores_gemma":[0.000076921,0.00008156364,0.0000278399,0.00007961266,0.00004376382,0.00006106729,0.0001009056,0.00008790125,0.005700539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003550545,"about_ca_system_score_gemma":0.00002284302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002105328,"about_ca_topic_score_gemma":0.0001923058,"domain_scores_codex":[0.9991413,0.00008661514,0.0001084418,0.0002577344,0.00003637027,0.0003695419],"domain_scores_gemma":[0.9996245,0.00005749277,0.00002167867,0.0001964472,0.00003174972,0.00006816137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003524966,0.0003066777,0.3444887,0.0000409276,0.0002520673,0.00001888669,0.00216916,0.00001644261,0.5821549,0.0005717431,0.008403703,0.06122423],"study_design_scores_gemma":[0.002230898,0.001714045,0.4185012,0.00009679289,0.00004241761,0.00001804424,0.0004536952,0.000001806479,0.5182897,0.0004379766,0.05783531,0.0003781492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965215,0.0005588593,0.00001088764,0.001355531,0.0001407075,0.0004528168,0.0001740405,0.00005285774,0.0007327862],"genre_scores_gemma":[0.9933943,0.00003125214,0.00003257617,0.000106597,0.00002252933,0.00004782976,0.0000502947,0.000009793306,0.006304825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07401242,"threshold_uncertainty_score":0.9950736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008331918814825083,"score_gpt":0.2548387127790052,"score_spread":0.2465067939641801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}