{"id":"W2946003074","doi":"10.1002/jsp2.1055","title":"Mesenchymal stem cell therapies for intervertebral disc degeneration: Consideration of the degenerate niche","year":2019,"lang":"en","type":"article","venue":"JOR Spine","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; Daphne Jackson Trust; Sheffield Hallam University","keywords":"Mesenchymal stem cell; Intervertebral disc; Degeneration (medical); Niche; Medicine; Stem cell; Pathology; Anatomy; Biology; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001464053,0.0001501792,0.0003251957,0.00005214444,0.00005624917,0.000017705,0.0001108165,0.00009435563,0.0004551639],"category_scores_gemma":[0.00003310697,0.00008996531,0.000252741,0.0001068516,0.00006032525,0.0001097621,0.00005365802,0.0001097942,0.00003695369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002928546,"about_ca_system_score_gemma":0.0000839123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001346457,"about_ca_topic_score_gemma":0.0000515605,"domain_scores_codex":[0.9990048,0.00005725635,0.0003887477,0.0002254285,0.0001460325,0.0001777522],"domain_scores_gemma":[0.9992592,0.00001024674,0.0001600529,0.0003626287,0.0001647179,0.00004313817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005103671,0.0001619912,0.00985703,0.0002037942,0.00007410976,0.000002136225,0.0003784515,0.000042707,0.9735749,0.004664958,0.008670001,0.002318926],"study_design_scores_gemma":[0.002506743,0.001329731,0.0604346,0.00009284807,0.0000992125,0.00002778644,0.0002806253,0.005555785,0.9282181,0.00009878117,0.001216166,0.000139568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890507,0.0008146239,0.003440068,0.003578944,0.0007660062,0.0008227577,0.00001911011,0.00002449551,0.001483258],"genre_scores_gemma":[0.9838009,0.00001764382,0.003127656,0.001357759,0.0002186515,0.00005097999,0.00003706988,0.00002162364,0.01136771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05057757,"threshold_uncertainty_score":0.4983725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0222846019733263,"score_gpt":0.2725008178483751,"score_spread":0.2502162158750488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}