{"id":"W2946091155","doi":"10.1002/jcp.28813","title":"Neuropathological and genomic characterization of glioblastoma‐induced rat model: How similar is it to humans for targeted therapy?","year":2019,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; CancerCare Manitoba","funders":"Royan Institute; Kashan University of Medical Sciences","keywords":"Glioblastoma; Brain tumor; Neuroscience; Mechanism (biology); Pathological; Computational biology; Biology; Magnetic resonance imaging; U87; Tumor progression; Genomics; Bioinformatics; Gene; Cancer research; Medicine; Pathology; Genome; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001157856,0.0001327551,0.000511626,0.0001331701,0.00002629586,0.000007535599,0.00006900398,0.00009005101,0.0000466722],"category_scores_gemma":[0.00002171895,0.00009153841,0.0001579197,0.00006448128,0.00002368771,0.00005240929,0.00002437237,0.00009537797,0.000003895905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002056245,"about_ca_system_score_gemma":0.00003566461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.036046e-7,"about_ca_topic_score_gemma":1.261426e-7,"domain_scores_codex":[0.9992297,0.00005806444,0.0002855957,0.0001699268,0.0001045903,0.000152075],"domain_scores_gemma":[0.9992304,0.00004267668,0.0002957383,0.000151373,0.0001876165,0.00009219673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009635513,0.0002653867,0.0005605564,0.00003065237,0.00006662082,0.00002280723,0.0002668739,0.00008659195,0.9971955,0.00002138555,0.0002055745,0.0003144747],"study_design_scores_gemma":[0.003072825,0.006411876,0.03227764,0.00003373243,0.00008583295,0.00004636164,0.00003268652,0.00179861,0.9551179,0.0001129285,0.0009198206,0.00008981997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958461,0.0001461445,0.0003346687,0.003040526,0.0001490351,0.0004602617,0.00001445904,0.000003847102,0.000004978936],"genre_scores_gemma":[0.997842,0.0002053417,0.0002980442,0.001449694,0.0001171756,0.000008347783,0.00001275334,0.00001873837,0.00004795871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04207766,"threshold_uncertainty_score":0.3732828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02723139849329927,"score_gpt":0.2631548900719812,"score_spread":0.2359234915786819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}