{"id":"W2946101898","doi":"10.1534/genetics.119.302254","title":"Binding of an <i>X</i> -Specific Condensin Correlates with a Reduction in Active Histone Modifications at Gene Regulatory Elements","year":2019,"lang":"en","type":"article","venue":"Genetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Biology; Chromatin; Histone; Genetics; Condensin; Dosage compensation; Histone H4; Histone H1; Heterochromatin protein 1; Gene; Chromatin immunoprecipitation; Regulation of gene expression; Heterochromatin; Cell biology; Molecular biology; Gene expression; Promoter; Cohesin","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001005866,0.0002947713,0.0001727046,0.0002816474,0.0001641214,0.0002733959,0.0001514987,0.0002554405,0.002058136],"category_scores_gemma":[0.0001042126,0.0002180424,0.0001944737,0.0001127296,0.0002888239,0.00009854898,0.0002407021,0.0004612898,0.0003786004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004254684,"about_ca_system_score_gemma":0.0001212287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001959024,"about_ca_topic_score_gemma":0.002561581,"domain_scores_codex":[0.9998507,0.00001007731,0.000008496307,0.00005293359,0.00003833146,0.00003939157],"domain_scores_gemma":[0.9998034,0.00001980172,0.00006344889,0.00001624314,0.00001803187,0.00007924216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003011051,0.000005006669,0.0003359022,0.000008555028,0.000004018573,0.00001854473,0.000002839089,0.000006962495,0.999403,0.00001971348,0.00002252952,0.0001428175],"study_design_scores_gemma":[0.00001112877,0.0000737286,0.06851229,0.000003686694,0.00001315904,0.0002589328,0.00001696676,0.0003901811,0.9293569,0.00004085854,0.001318505,0.000003663614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947028,0.001096672,0.002274335,0.0001103423,0.00003342377,0.00001491286,0.0005028105,0.00008887269,0.001175938],"genre_scores_gemma":[0.9952393,0.0002439986,0.0006731823,0.00009337056,0.000009642687,0.00001578952,0.0005101716,0.00002693445,0.003187705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002058136,"threshold_uncertainty_score":0.006885171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007416956730033645,"score_gpt":0.2224433624113796,"score_spread":0.215026405681346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}