{"id":"W2946101898","doi":"10.1534/genetics.119.302254","title":"Binding of an <i>X</i> -Specific Condensin Correlates with a Reduction in Active Histone Modifications at Gene Regulatory Elements","year":2019,"lang":"en","type":"article","venue":"Genetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Biology; Chromatin; Histone; Genetics; Condensin; Dosage compensation; Histone H4; Histone H1; Heterochromatin protein 1; Gene; Chromatin immunoprecipitation; Regulation of gene expression; Heterochromatin; Cell biology; Molecular biology; Gene expression; Promoter; Cohesin","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007615906,0.0001185858,0.000129457,0.00006239671,0.00003978823,0.000006826036,0.0001107298,0.0001142167,0.0000147573],"category_scores_gemma":[0.000002289225,0.000124727,0.00002923252,0.00009311432,0.00007081577,0.000003319591,0.00006070476,0.00006011853,0.000009269202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008736133,"about_ca_system_score_gemma":0.00005190568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005387965,"about_ca_topic_score_gemma":0.00007424092,"domain_scores_codex":[0.9991615,0.00002884385,0.0002403138,0.0002966774,0.0001107372,0.0001618961],"domain_scores_gemma":[0.9992595,0.00000327593,0.0001705216,0.000443664,0.00007768124,0.00004533381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008268346,0.00007366476,0.002937635,0.000007614815,0.00002236294,6.313712e-7,0.0001436537,0.004240967,0.9916613,0.00003679845,0.00007812501,0.0007145376],"study_design_scores_gemma":[0.0008667181,0.0003386798,0.02250016,0.0000156517,0.00001638059,0.0000353292,0.0003402961,0.002718203,0.9723261,0.00005170534,0.0005856485,0.0002051423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988648,0.0003251228,0.0001055802,0.00001253388,0.0001142129,0.0002538631,0.000046511,0.000004830823,0.0002725154],"genre_scores_gemma":[0.9931241,0.0001997338,0.00575316,0.00001001124,0.00003225348,0.000009397329,0.0003727353,0.00002674165,0.0004719074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01956253,"threshold_uncertainty_score":0.5086219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007416956730033645,"score_gpt":0.2224433624113796,"score_spread":0.215026405681346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}