{"id":"W2946362644","doi":"10.1128/jb.00707-18","title":"Metabolomics Studies To Decipher Stress Responses in Mycobacterium smegmatis Point to a Putative Pathway of Methylated Amine Biosynthesis","year":2019,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Indian Institute of Science Education and Research Mohali; Indian Institute of Science Education and Research Pune; University of Hyderabad; Queen's University; Indian Council of Medical Research; University Grants Commission; Department of Science and Technology, Ministry of Science and Technology, India; Department of Biotechnology, Ministry of Science and Technology, India; Queen's University Belfast","keywords":"Biology; Biochemistry; Mycobacterium smegmatis; Metabolic pathway; Ectoine; Osmolyte; Biosynthesis; Metabolomics; Phenylpropanoid; Mycobacterium; Mycobacterium tuberculosis; Microbiology; Metabolism; Enzyme; Osmoprotectant; Bacteria; Proline; Amino acid; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001564825,0.000408871,0.0002990373,0.0005272052,0.000235902,0.0002534667,0.0000929541,0.0003445701,0.0005500907],"category_scores_gemma":[0.0001797678,0.00008024962,0.0003677913,0.0004425921,0.0001406658,0.0002564403,0.0002484081,0.0003204919,0.0001743692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002041979,"about_ca_system_score_gemma":0.0002363572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007465812,"about_ca_topic_score_gemma":0.001500385,"domain_scores_codex":[0.9999135,0.00001269579,0.000006736248,0.00002476134,0.0000248497,0.000017479],"domain_scores_gemma":[0.9999013,0.00002012245,0.00002621863,0.000008384261,0.00002538053,0.00001853799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001224522,0.00001472539,0.001920891,0.00008589405,0.00001417423,0.00006676663,0.00002911205,0.00004228339,0.9948249,0.00002798026,0.00001559997,0.00283525],"study_design_scores_gemma":[0.000009160366,0.0007616284,0.0850824,0.00002921184,0.00009309054,0.0007501199,0.00023078,0.0009762809,0.9078093,0.0002997106,0.003938427,0.00001996245],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794585,0.007696161,0.008611797,0.0001818497,0.0000436816,0.00007428054,0.002444073,0.00008295503,0.001406814],"genre_scores_gemma":[0.9860333,0.002637529,0.008630381,0.00008873684,0.00001230674,0.00002862127,0.001433038,0.0000122393,0.001123854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007465812,"threshold_uncertainty_score":0.001840234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0328175550472716,"score_gpt":0.3408790881366232,"score_spread":0.3080615330893516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}