{"id":"W2946375410","doi":"10.3791/59965","title":"Serum Free Production of Three-dimensional Human Hepatospheres from Pluripotent Stem Cells","year":2019,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"Medical Research Council; UK Regenerative Medicine Platform","keywords":"Induced pluripotent stem cell; Embryonic stem cell; Stem cell; Cell biology; Biology; Human Induced Pluripotent Stem Cells; Regenerative medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003239216,0.0003473885,0.0002097981,0.0002895054,0.0001336737,0.0003817322,0.0001646197,0.0002354227,0.0009811168],"category_scores_gemma":[0.0001874168,0.0001191008,0.0002861234,0.0002200971,0.0001772957,0.0001673137,0.000416279,0.0002957802,0.0005002169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001490197,"about_ca_system_score_gemma":0.0002668333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007385007,"about_ca_topic_score_gemma":0.001647978,"domain_scores_codex":[0.9998764,0.00001641141,0.00001589171,0.0000137125,0.00004811929,0.00002942887],"domain_scores_gemma":[0.9997714,0.00004818596,0.0000321411,0.00003991368,0.00004463385,0.00006361214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003661397,0.00001082464,0.0002073053,0.00005745812,0.000003894585,0.00008598785,0.00003832617,0.000206704,0.9965078,0.0001328191,0.0001094475,0.002602803],"study_design_scores_gemma":[0.00001177989,0.0001074739,0.002135978,0.00001268856,0.00001876217,0.0001974369,0.00003209487,0.001067908,0.9912408,0.00005535441,0.005112511,0.000007127784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.918866,0.00362612,0.06258447,0.0002551803,0.0001787629,0.0003332371,0.003233999,0.0009025206,0.01001973],"genre_scores_gemma":[0.9680942,0.001773169,0.0226835,0.00009159176,0.00002242869,0.00008682848,0.003453548,0.0001123163,0.003682469],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.0009811168,"threshold_uncertainty_score":0.003282189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03158522351948905,"score_gpt":0.3592480185708107,"score_spread":0.3276627950513216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}