{"id":"W2946422050","doi":"10.1371/journal.ppat.1007731","title":"Structure and assembly of pilotin-dependent and -independent secretins of the type II secretion system","year":2019,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"French Infrastructure for Integrated Structural Biology; Centre National de la Recherche Scientifique; Agence Nationale de la Recherche; Natural Sciences and Engineering Research Council of Canada; Infrastructures en Biologie Santé et Agronomie","keywords":"Periplasmic space; Vibrio vulnificus; Bacterial outer membrane; Secretion; Biology; Inner membrane; Cell biology; Cell envelope; Secretin; Type VI secretion system; Membrane protein; Biophysics; Biochemistry; Virulence; Membrane; Bacteria; Escherichia coli; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001184157,0.0001035276,0.0001775296,0.00002469222,0.0000606195,0.000007587774,0.0001119373,0.00009187575,0.000009839727],"category_scores_gemma":[0.00007665627,0.00007462066,0.00003442806,0.0000579631,0.00006720606,0.000002875833,0.0004370548,0.00007030158,7.263154e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001180605,"about_ca_system_score_gemma":0.00004305832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001056398,"about_ca_topic_score_gemma":0.0000187115,"domain_scores_codex":[0.9991691,0.00008467823,0.0001611622,0.0002281645,0.0002164074,0.000140482],"domain_scores_gemma":[0.9993936,0.00001178772,0.0001208648,0.0002852229,0.0001482074,0.0000403255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005786823,0.00002002719,0.04200726,0.0002499313,0.00008099288,6.719154e-7,0.0001218557,0.000003705243,0.9573058,0.00004816703,0.00000981337,0.00009385838],"study_design_scores_gemma":[0.0004239471,0.0006074582,0.1765224,0.00007746708,0.0000457656,0.00001674945,0.000371969,0.00009263287,0.8216667,0.000008075092,0.00006607382,0.0001008032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986981,0.0004274193,0.000007401994,0.00003669295,0.00009290245,0.0003197068,0.0001481255,0.000004533627,0.0002651621],"genre_scores_gemma":[0.9995781,0.000139288,0.00006996343,0.000009589456,0.00004133886,0.0000034913,0.0000198845,0.00001272378,0.0001256837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1356392,"threshold_uncertainty_score":0.3042942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008644739152479678,"score_gpt":0.2218901845144593,"score_spread":0.2132454453619796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}