{"id":"W2946475694","doi":"10.1111/jvh.13132","title":"Efficacy and safety of a two‐drug direct‐acting antiviral agent regimen ruzasvir 180 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4, 5 or 6","year":2019,"lang":"en","type":"article","venue":"Journal of Viral Hepatitis","topic":"Hepatitis C virus research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre; University of Toronto","funders":"Merck Sharp and Dohme","keywords":"Tolerability; Medicine; Regimen; Ribavirin; Adverse effect; Internal medicine; Hepatitis C virus; Drug; Hepatitis C; Gastroenterology; Cirrhosis; Pharmacology; Virology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001163127,0.0005462968,0.000942298,0.000203531,0.0002137412,0.0003164635,0.0003832675,0.000849183,0.001666092],"category_scores_gemma":[0.0009756767,0.0003401395,0.00065316,0.0001380498,0.0003779338,0.0004602673,0.0002289758,0.001048066,0.0003676185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004025669,"about_ca_system_score_gemma":0.0003953224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005105272,"about_ca_topic_score_gemma":0.0009461666,"domain_scores_codex":[0.9993376,0.0003617136,0.00005769376,0.00008791025,0.00009130555,0.00006377316],"domain_scores_gemma":[0.999619,0.00008263463,0.0001036771,0.00003523169,0.00003254541,0.0001269043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.619681,0.04504845,0.02628692,0.0006984713,0.001215462,0.0002399444,0.000446653,0.001364487,0.07105951,0.000137752,0.000966153,0.2328552],"study_design_scores_gemma":[0.1269403,0.7750252,0.08498951,0.00004128314,0.0006285818,0.0003439371,0.00007865192,0.00162367,0.008338319,0.00006943366,0.001880277,0.00004073639],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982386,0.000822562,0.0001109231,0.00005712563,0.00001166157,0.0001643881,0.0001228895,0.00001662248,0.0004553215],"genre_scores_gemma":[0.9985024,0.0003494987,0.0002529063,0.00007641681,0.00003154949,0.0001367746,0.0002069629,0.000003444361,0.000440223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001666092,"threshold_uncertainty_score":0.006151259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01534624440452465,"score_gpt":0.2995609193513389,"score_spread":0.2842146749468143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}