{"id":"W2946516840","doi":"10.1073/pnas.1818820116","title":"Role for polo-like kinase 4 in mediation of cytokinesis","year":2019,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"National Cancer Institute; Entertainment Industry Foundation; Tower Cancer Research Foundation; University of Southern California; National Institute of Allergy and Infectious Diseases; Avon Foundation for Women; Breast Cancer Research Foundation; Office of the Provost, University of South Carolina; California Institute for Regenerative Medicine; Dr. Miriam and Sheldon G. Adelson Medical Research Foundation","keywords":"Cytokinesis; Midbody; Cell biology; Telophase; Anaphase; Polo-like kinase; Centrosome; Mitosis; Aurora B kinase; PLK1; Biology; Cell cycle; Cell division; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047103,0.0000444102,0.00008203306,0.00007116022,0.00002126279,0.000002980041,0.0002979105,0.00007412261,0.000002526014],"category_scores_gemma":[0.0001709628,0.00003260088,0.00005004375,0.0001867649,0.000135767,0.00001217273,0.00006128017,0.00003056094,2.095097e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007107024,"about_ca_system_score_gemma":0.00002599098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004901419,"about_ca_topic_score_gemma":3.796277e-7,"domain_scores_codex":[0.9993767,0.000002277613,0.0001822223,0.0001319027,0.0002332073,0.00007372288],"domain_scores_gemma":[0.9995944,0.00002022478,0.0002188571,0.00000663714,0.00015015,0.000009701404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002103693,0.00002351046,0.0202919,0.00004341149,0.000004594292,1.335397e-10,0.00003146458,0.000066911,0.9761214,0.003118064,0.0001306943,0.0001470702],"study_design_scores_gemma":[0.0002069409,0.00006872398,0.04343485,0.00002163603,0.000003596182,5.658218e-7,0.00009307405,0.0006320372,0.9515516,0.003544504,0.0004026474,0.00003980627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985284,0.0001233024,0.000002181156,0.000353137,0.00001334215,0.0001738139,0.00002178837,8.613965e-7,0.0007832293],"genre_scores_gemma":[0.9989327,0.00004344167,0.0007739561,0.0001095508,0.00003283225,0.00000841899,0.000001016023,0.00000232124,0.00009582743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02456973,"threshold_uncertainty_score":0.1329425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.012681134101094,"score_gpt":0.2716270835963522,"score_spread":0.2589459494952582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}