{"id":"W2946516840","doi":"10.1073/pnas.1818820116","title":"Role for polo-like kinase 4 in mediation of cytokinesis","year":2019,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"National Cancer Institute; Entertainment Industry Foundation; Tower Cancer Research Foundation; University of Southern California; National Institute of Allergy and Infectious Diseases; Avon Foundation for Women; Breast Cancer Research Foundation; Office of the Provost, University of South Carolina; California Institute for Regenerative Medicine; Dr. Miriam and Sheldon G. Adelson Medical Research Foundation","keywords":"Cytokinesis; Midbody; Cell biology; Telophase; Anaphase; Polo-like kinase; Centrosome; Mitosis; Aurora B kinase; PLK1; Biology; Cell cycle; Cell division; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002121882,0.000474616,0.0002193741,0.0002177607,0.0002901478,0.0004957587,0.0002941111,0.00028962,0.001434934],"category_scores_gemma":[0.0001896277,0.0001401923,0.0002590392,0.0000710129,0.0003849601,0.0003198573,0.0002268683,0.0004585178,0.0003919414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006681675,"about_ca_system_score_gemma":0.0003863813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000391936,"about_ca_topic_score_gemma":0.0004470537,"domain_scores_codex":[0.9999112,0.00002305063,0.000007603001,0.00001676027,0.00001462401,0.0000266832],"domain_scores_gemma":[0.9999266,0.00001781531,0.00002142382,0.000007288865,0.000006942883,0.0000199635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001087271,0.00009640113,0.001253623,0.000195383,0.0000256338,0.0004546306,0.00002783787,0.0006029836,0.989664,0.00098836,0.0001469252,0.005457019],"study_design_scores_gemma":[0.0002078567,0.0005877651,0.009443904,0.00002339316,0.00006212571,0.0006889318,0.00008506783,0.004113171,0.9758083,0.0006373393,0.008328543,0.000013705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9742654,0.01542534,0.003525991,0.0007289157,0.0001017395,0.00005101137,0.0003181013,0.0001255145,0.005458085],"genre_scores_gemma":[0.9943802,0.002540191,0.0007416186,0.00006511602,0.00001572995,0.000022959,0.0001885544,0.000005532845,0.002040024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001434934,"threshold_uncertainty_score":0.004847944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.012681134101094,"score_gpt":0.2716270835963522,"score_spread":0.2589459494952582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}