{"id":"W2946655075","doi":"10.23860/diss-bian-ke-2019","title":"DNA damage, repair and mutational spectrum","year":2019,"lang":"en","type":"dissertation","venue":"","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Cancer Institute; National Institutes of Health; Alberta Innovates; Rhode Island Foundation; Howard Hughes Medical Institute","keywords":"DNA damage; DNA; DNA repair; Genetics; Epigenetics; Mutation; Mutagenesis; Genome instability; AlkB; DNA replication; Biology; Chemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002854439,0.0002241337,0.000286987,0.00175762,0.0004335428,0.0009245322,0.0004047814,0.0005468962,0.005375946],"category_scores_gemma":[0.0005189214,0.0001724663,0.0002001008,0.0007243414,0.0004234653,0.00067181,0.000550774,0.0004899944,0.001118506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006121633,"about_ca_system_score_gemma":0.0002093878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005908362,"about_ca_topic_score_gemma":0.0003496447,"domain_scores_codex":[0.9995986,0.00003380171,0.00001802785,0.0001136333,0.0001858435,0.00005007636],"domain_scores_gemma":[0.9996978,0.00004355709,0.00007243468,0.00002944018,0.0001073933,0.00004942627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007093583,0.00018634,0.02553878,0.0008398045,0.0000827607,0.0006077154,0.0006335774,0.001964933,0.772312,0.04570473,0.002717782,0.1487022],"study_design_scores_gemma":[0.00005278986,0.001882214,0.2552667,0.0004512775,0.0001963758,0.01150586,0.001882485,0.005906979,0.5039387,0.07421546,0.1445543,0.0001467799],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.7895547,0.09838069,0.01844426,0.001250934,0.0002250476,0.0001151542,0.002003853,0.0003423982,0.08968285],"genre_scores_gemma":[0.9585648,0.01705799,0.002850967,0.0002312845,0.00008530758,0.00007138449,0.0006765078,0.0000391254,0.02042257],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.005375946,"threshold_uncertainty_score":0.01798433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004927389680590886,"score_gpt":0.2413692073857026,"score_spread":0.2364418177051117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}