{"id":"W2946847163","doi":"10.1136/annrheumdis-2019-eular.3249","title":"SAT0098 ANTIBODIES AGAINST CITRULLINATED ANTIGENS ARE ASSOCIATED WITH TREATMENT RESPONSE IN ACPA-NEGATIVE RHEUMATOID ARTHRITIS PATIENTS","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"NIHR Sheffield Biomedical Research Centre; Canadian Institutes of Health Research; Eli Lilly Canada; University of Manchester; Bristol-Myers Squibb; Manchester Biomedical Research Centre; Bristol-Myers Squibb Canada","keywords":"Medicine; Autoantibody; Rheumatoid arthritis; Internal medicine; Immunology; Antigen; Rheumatology; Antibody; Adalimumab; Gastroenterology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002632611,0.0002698443,0.0002873514,0.00065957,0.0002923105,0.0004630597,0.0002691158,0.0005565794,0.00263676],"category_scores_gemma":[0.002174756,0.0001690243,0.000294122,0.0007112646,0.0002206181,0.0002385269,0.0001593171,0.0005120406,0.000293644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001639749,"about_ca_system_score_gemma":0.0001230451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001145422,"about_ca_topic_score_gemma":0.001030102,"domain_scores_codex":[0.9996485,0.0001156675,0.00004892457,0.00005356547,0.00007107529,0.00006226017],"domain_scores_gemma":[0.998393,0.000532625,0.0007271887,0.00004791986,0.0001111139,0.0001880768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007131455,0.00008132894,0.9932545,0.00001919952,0.00007376391,0.000519306,0.00006193154,0.00003401143,0.002341275,0.00002151267,0.0001004062,0.002779723],"study_design_scores_gemma":[0.00001788024,0.0001982028,0.9975452,0.000006891448,0.00004778032,0.001579386,0.00008001064,0.0001504341,0.0001537457,0.00002414602,0.0001928931,0.000003388854],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998484,0.0005255045,0.00004135126,0.00005358175,0.000009876216,0.000003365784,0.00006917304,0.000003637788,0.0008095266],"genre_scores_gemma":[0.9995888,0.00007533413,0.00003241418,0.00003015103,0.00001397407,0.000002468931,0.00008026453,0.00000122547,0.0001753672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00263676,"threshold_uncertainty_score":0.008820832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02953123121134983,"score_gpt":0.2987882637972616,"score_spread":0.2692570325859118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}