{"id":"W2946912776","doi":"10.1177/1535370219851243","title":"The cytoprotective impact of yes-associated protein 1 after ischemia-reperfusion injury in AC16 human cardiomyocytes","year":2019,"lang":"en","type":"article","venue":"Experimental Biology and Medicine","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Cytoprotection; Reperfusion injury; Cell biology; Hippo signaling pathway; Ischemia; Signal transduction; Wnt signaling pathway; Biology; Apoptosis; Medicine; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000325582,0.0001428754,0.0002286422,0.00003799622,0.00007081871,0.000002625432,0.00009193475,0.0001922027,0.00004952692],"category_scores_gemma":[0.00005955587,0.0000843434,0.00006786222,0.00006103063,0.0002875155,0.000002793576,0.00008716062,0.000125468,0.000002659868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002988992,"about_ca_system_score_gemma":0.00003523028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002819187,"about_ca_topic_score_gemma":0.00001221771,"domain_scores_codex":[0.999178,0.0001213407,0.0001980981,0.0002492136,0.00005878721,0.0001945454],"domain_scores_gemma":[0.9996326,0.00001609713,0.00008193439,0.0001914144,0.00003225381,0.00004567872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004313609,0.00004508314,0.0184452,0.0000044001,0.0000583158,0.000001412271,0.0003427405,5.040413e-7,0.9803003,0.00002047539,0.00002172838,0.000328486],"study_design_scores_gemma":[0.001042104,0.002845305,0.004622832,0.00006951084,0.000005532555,0.000003780355,0.0003690984,0.000003391641,0.990597,0.00004583292,0.0002934045,0.0001022552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994862,0.004207227,0.000001822055,0.00004275638,0.0000656499,0.0003699938,0.00001312582,0.000005905135,0.0004315479],"genre_scores_gemma":[0.9994192,0.00005708346,0.000008553662,0.00004074935,0.00008659724,0.00007338562,0.00005895366,0.000009519141,0.0002459163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01382237,"threshold_uncertainty_score":0.3439424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005731613815051093,"score_gpt":0.3090263312140591,"score_spread":0.303294717399008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}