{"id":"W2946985211","doi":"10.1084/jem.20182213","title":"The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors","year":2019,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Sveučilište u Rijeci; Medical Research Council; NHS Blood and Transplant; Hrvatska Zaklada za Znanost; European Regional Development Fund; Deutsche Forschungsgemeinschaft","keywords":"Biology; MHC class I; Major histocompatibility complex; Cell biology; MHC restriction; Receptor; Cytotoxic T cell; Immune receptor; Immune system; Virology; Immunology; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009662435,0.0003050039,0.0001346697,0.0001343707,0.0001302029,0.0002844355,0.0002264436,0.0003056583,0.0007870402],"category_scores_gemma":[0.0001191503,0.0001186318,0.0001655977,0.00008163601,0.0002918688,0.0001678426,0.0003081958,0.000588036,0.0002256316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006322309,"about_ca_system_score_gemma":0.0001795929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009271465,"about_ca_topic_score_gemma":0.001004822,"domain_scores_codex":[0.9998624,0.00002232403,0.000008071,0.0000203189,0.00004758696,0.00003921414],"domain_scores_gemma":[0.9999374,0.000008962365,0.00001853392,0.00001262147,0.000004293871,0.00001824696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000320767,0.000006297997,0.0002274606,0.00001214183,0.000002965041,0.00004457802,0.000007679342,0.0001037902,0.9984781,0.0003539571,0.00002384913,0.0007071072],"study_design_scores_gemma":[0.000008494728,0.0001021859,0.002535241,0.000004267769,0.00000853376,0.0002781,0.00001708355,0.002014713,0.9918478,0.0001142222,0.00306562,0.000003781676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946736,0.0006590734,0.002791009,0.0001008334,0.00002488019,0.00001109603,0.00007097865,0.00005379607,0.001614734],"genre_scores_gemma":[0.9972302,0.0001329032,0.001311598,0.0000218113,0.00000389658,0.000004719068,0.00008979911,0.00001056306,0.001194542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009271465,"threshold_uncertainty_score":0.004587173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0125299384241894,"score_gpt":0.2460299779146966,"score_spread":0.2335000394905072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}