{"id":"W2947042873","doi":"10.1016/j.mehy.2019.109249","title":"Hypoxia inducible factors as mediators of reactive oxygen/nitrogen species homeostasis in physiological normoxia","year":2019,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"High Altitude and Hypoxia","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hypoxia (environmental); Homeostasis; Reactive oxygen species; Oxygen; Reactive nitrogen species; Biology; Chemistry; Endocrinology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000767548,0.0003853464,0.0002030799,0.0004865496,0.0003401418,0.0007167468,0.0005655678,0.0005337343,0.0008423806],"category_scores_gemma":[0.0004121888,0.0001208645,0.000144057,0.0001825676,0.001071918,0.0006457403,0.0002644339,0.0004434397,0.0001332663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003064435,"about_ca_system_score_gemma":0.0002344463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003421525,"about_ca_topic_score_gemma":0.0003392075,"domain_scores_codex":[0.9998944,0.00004277989,0.000006291341,0.00001216529,0.00002226863,0.00002209325],"domain_scores_gemma":[0.9997262,0.0001265861,0.00004732908,0.00001575614,0.00003464621,0.00004937603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.008935808,0.0008690287,0.02393248,0.001610382,0.000176664,0.01018925,0.002526625,0.002954158,0.6381128,0.2201674,0.004605424,0.08592007],"study_design_scores_gemma":[0.0007513948,0.004599179,0.1268563,0.0005512002,0.0004740813,0.008809212,0.005463528,0.01035181,0.4802715,0.2298439,0.1318298,0.0001981472],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7431831,0.1736636,0.03353363,0.0196711,0.001943768,0.0001604319,0.0003320262,0.0001623222,0.02735003],"genre_scores_gemma":[0.9610848,0.02655232,0.003377153,0.001064988,0.001501508,0.00007268062,0.0001573892,0.000006793453,0.00618229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008423806,"threshold_uncertainty_score":0.004059196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02089713372392377,"score_gpt":0.2560451932455051,"score_spread":0.2351480595215813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}