{"id":"W2947084022","doi":"10.1136/annrheumdis-2019-eular.3082","title":"FRI0132 LONG-TERM SAFETY AND EFFICACY OF UPADACITINIB IN PATIENTS WITH RHEUMATOID ARTHRITIS AND AN INADEQUATE RESPONSE TO CSDMARDS: RESULTS AT 60 WEEKS FROM THE SELECT-NEXT STUDY","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Rheumatoid arthritis; Adverse effect; Internal medicine; Placebo; Randomized controlled trial; Safety profile; Surgery; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001577319,0.0007951004,0.00213722,0.0003098536,0.0002581597,0.0009526619,0.0004441316,0.0008055196,0.002289067],"category_scores_gemma":[0.001460357,0.0002678347,0.002587518,0.0003484604,0.0005094616,0.0008108122,0.0002705078,0.001897256,0.0006051427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007155283,"about_ca_system_score_gemma":0.0007080329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001067252,"about_ca_topic_score_gemma":0.002502061,"domain_scores_codex":[0.9994948,0.0001603197,0.00004180484,0.00008888722,0.0000941756,0.0001199897],"domain_scores_gemma":[0.9989906,0.0002562965,0.0003077019,0.00009636726,0.00009636358,0.0002527112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8077824,0.006685044,0.03822247,0.001399705,0.008349189,0.0003776151,0.0001754178,0.002104678,0.01574602,0.0002545748,0.004358781,0.1145442],"study_design_scores_gemma":[0.4351148,0.2592986,0.2714673,0.0003020459,0.01426808,0.001649046,0.0003214057,0.0034529,0.005482465,0.0004342044,0.007982948,0.0002262711],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913875,0.005338699,0.0001493635,0.000261644,0.00007070762,0.0001101502,0.001486642,0.00003378157,0.001161486],"genre_scores_gemma":[0.9939355,0.001790075,0.0002169166,0.0003489486,0.0001172347,0.0001112041,0.002525517,0.00001410972,0.0009403932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002289067,"threshold_uncertainty_score":0.00834173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02221680218042602,"score_gpt":0.2995138289043116,"score_spread":0.2772970267238855,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}