{"id":"W2947095069","doi":"10.1080/07388551.2019.1620677","title":"Bioproduction of fumaric acid: an insight into microbial strain improvement strategies","year":2019,"lang":"en","type":"review","venue":"Critical Reviews in Biotechnology","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bioproduction; Fumaric acid; Rhizopus oryzae; Bioprocess; Biochemistry; Chemistry; Biology; Biotechnology; Fermentation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007537452,0.001276912,0.0009067717,0.001165575,0.0002259379,0.001390273,0.0005072978,0.000816884,0.0005525866],"category_scores_gemma":[0.0003943151,0.0003350584,0.0009578861,0.001146992,0.0002910225,0.00124671,0.000557542,0.001316851,0.0005248146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005944949,"about_ca_system_score_gemma":0.0005050405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007472859,"about_ca_topic_score_gemma":0.001046162,"domain_scores_codex":[0.9996247,0.00006230258,0.00004531749,0.00008841533,0.0001240797,0.00005524749],"domain_scores_gemma":[0.9998434,0.00003298919,0.00003918259,0.00001454284,0.00005143488,0.00001835211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001106253,0.0003172959,0.001149314,0.00320305,0.00008034248,0.0005272842,0.0001514897,0.001480634,0.8388316,0.002602728,0.000505408,0.1510403],"study_design_scores_gemma":[0.00006972638,0.002827499,0.007409693,0.001193225,0.0005740428,0.002933321,0.0006597417,0.005808928,0.8329176,0.003202513,0.1422877,0.0001160424],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2823835,0.5889133,0.1082001,0.0034314,0.0004934235,0.0004231187,0.0007710456,0.0004446513,0.0149396],"genre_scores_gemma":[0.4351328,0.4510315,0.1069645,0.0006123932,0.0001543933,0.0002180101,0.001115271,0.00009136735,0.00467988],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001390273,"threshold_uncertainty_score":0.004313409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03102069156883836,"score_gpt":0.3392573701436623,"score_spread":0.3082366785748239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}