{"id":"W2947212862","doi":"10.7554/elife.47900","title":"Reality check for transposon enhancers","year":2019,"lang":"en","type":"article","venue":"eLife","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; University of British Columbia","funders":"","keywords":"Reality check; Transposable element; Enhancer; Computational biology; Biology; Genetics; Genome; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00175725,0.0006516731,0.0007726391,0.0008514845,0.0008989786,0.001092522,0.001109201,0.001259602,0.0175226],"category_scores_gemma":[0.004667453,0.0007026882,0.0009951375,0.0004179912,0.0008387642,0.001408384,0.001801978,0.003811086,0.005139302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007549713,"about_ca_system_score_gemma":0.0005883261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001329968,"about_ca_topic_score_gemma":0.003182447,"domain_scores_codex":[0.9980731,0.0002500822,0.0001797878,0.0005217443,0.0006801344,0.0002952092],"domain_scores_gemma":[0.9952141,0.002364897,0.0003424882,0.001055195,0.000640481,0.0003827829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001693906,0.0001009993,0.001721832,0.0001732498,0.00004010682,0.0004313611,0.0001687129,0.0001542464,0.9821767,0.003723869,0.001317511,0.009822004],"study_design_scores_gemma":[0.00005976663,0.0003063326,0.00405736,0.00006565414,0.00008170736,0.001080111,0.0002058211,0.001228506,0.9574522,0.001960223,0.03345777,0.00004454833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7671885,0.003971661,0.1659143,0.005007782,0.002119446,0.0006296115,0.004794562,0.007591085,0.04278316],"genre_scores_gemma":[0.8773377,0.001089933,0.06662788,0.0038633,0.000134597,0.000289025,0.006837532,0.002475717,0.04134433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0175226,"threshold_uncertainty_score":0.05861896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008432916332853967,"score_gpt":0.3176137452056434,"score_spread":0.3091808288727895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}