{"id":"W2947213077","doi":"10.1016/s1473-3099(19)30001-5","title":"Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study","year":2019,"lang":"en","type":"article","venue":"The Lancet Infectious Diseases","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":216,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; European and Developing Countries Clinical Trials Partnership; Global Health Innovative Technology Fund; Ministerie van Buitenlandse Zaken; University of Cape Town; Bundesministerium für Bildung und Forschung; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Department of Science and Technology, Ministry of Science and Technology, India; Department of Foreign Affairs and Trade, Australian Government; South African Medical Research Council; National Department of Health; National Research Foundation; National Research Foundation of Korea; Wellcome Trust; Department for International Development, UK Government; Bill and Melinda Gates Foundation","keywords":"Medicine; Lipoarabinomannan; Tuberculosis; Internal medicine; Urine; Gold standard (test); Human immunodeficiency virus (HIV); Prospective cohort study; Mycobacterium tuberculosis; Point-of-care testing; Tuberculosis diagnosis; Point of care; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006631243,0.0004177725,0.0003704652,0.002232414,0.0003753981,0.0009441125,0.0007919411,0.0008928198,0.0004694343],"category_scores_gemma":[0.01871069,0.000332913,0.0005183035,0.001088918,0.0004447215,0.0008775381,0.0006402505,0.0005615526,0.0002166781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00073544,"about_ca_system_score_gemma":0.0003600006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002087011,"about_ca_topic_score_gemma":0.00248575,"domain_scores_codex":[0.9946502,0.001589992,0.0007138664,0.0009316231,0.001883205,0.0002311017],"domain_scores_gemma":[0.9897857,0.003248309,0.003599074,0.0006188183,0.002427642,0.0003203408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002719919,0.00005692132,0.9954399,0.0000358628,0.00007984742,0.00006716239,0.00008768838,0.00008905271,0.000476386,0.00002680248,0.00006006244,0.003308411],"study_design_scores_gemma":[0.00006246248,0.0009577006,0.9880143,0.00007303384,0.0002954288,0.002453951,0.0002607013,0.004823577,0.002364237,0.00007405954,0.0006047312,0.00001585173],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947433,0.002384416,0.00145108,0.0001298843,0.00002701004,0.00009335911,0.0003899185,0.00001990285,0.0007611128],"genre_scores_gemma":[0.998071,0.0002749126,0.001228317,0.00005383105,0.00002048161,0.00002022242,0.0002560027,0.000002657971,0.00007265581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006631243,"threshold_uncertainty_score":0.03506976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01928433783962478,"score_gpt":0.3129618663975524,"score_spread":0.2936775285579276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}