{"id":"W2947213077","doi":"10.1016/s1473-3099(19)30001-5","title":"Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study","year":2019,"lang":"en","type":"article","venue":"The Lancet Infectious Diseases","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":216,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; European and Developing Countries Clinical Trials Partnership; Global Health Innovative Technology Fund; Ministerie van Buitenlandse Zaken; University of Cape Town; Bundesministerium für Bildung und Forschung; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Department of Science and Technology, Ministry of Science and Technology, India; Department of Foreign Affairs and Trade, Australian Government; South African Medical Research Council; National Department of Health; National Research Foundation; National Research Foundation of Korea; Wellcome Trust; Department for International Development, UK Government; Bill and Melinda Gates Foundation","keywords":"Medicine; Lipoarabinomannan; Tuberculosis; Internal medicine; Urine; Gold standard (test); Human immunodeficiency virus (HIV); Prospective cohort study; Mycobacterium tuberculosis; Point-of-care testing; Tuberculosis diagnosis; Point of care; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002588209,0.0002358165,0.0008792234,0.0001087255,0.0001375225,0.00002631914,0.0002267211,0.00005706725,0.0001196288],"category_scores_gemma":[0.007217863,0.0001361655,0.0001925669,0.0003219771,0.0001077193,0.0001105623,0.00009528278,0.0002111965,0.00009159615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007871554,"about_ca_system_score_gemma":0.000156093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004711836,"about_ca_topic_score_gemma":0.0005558985,"domain_scores_codex":[0.9983878,0.0001157612,0.0002996927,0.0003778363,0.0002656431,0.000553294],"domain_scores_gemma":[0.9917049,0.006832514,0.000138722,0.0008173138,0.0003014359,0.0002051554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007945073,0.001720638,0.9899241,0.0006161883,0.0003468163,0.000005850935,0.0007273093,0.0001190001,0.0002874288,0.0001011232,0.004379763,0.0009773236],"study_design_scores_gemma":[0.006216987,0.005627326,0.9844303,0.0001867302,0.0005849642,0.00005894254,0.001281429,0.0002079905,0.00007835264,0.0001030549,0.001040789,0.0001831916],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903402,0.0008821687,0.0001134004,0.003436335,0.00009832302,0.003539789,0.0003411724,0.000159357,0.001089201],"genre_scores_gemma":[0.9971894,0.0001817622,0.00005376009,0.001077811,0.000422773,0.0008328782,0.000109289,0.00004324271,0.00008909311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006959042,"threshold_uncertainty_score":0.8640978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01928433783962478,"score_gpt":0.3129618663975524,"score_spread":0.2936775285579276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}