{"id":"W2947254149","doi":"10.15698/mic2019.06.680","title":"Functional link between mitochondria and Rnr3, the minor catalytic subunit of yeast ribonucleotide reductase","year":2019,"lang":"en","type":"article","venue":"Microbial Cell","topic":"Metal-Catalyzed Oxygenation Mechanisms","field":"Chemistry","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"North West Cancer Research","keywords":"Ribonucleotide reductase; Biology; Mitochondrion; DNA damage; Saccharomyces cerevisiae; Mitochondrial DNA; Cell biology; Protein subunit; DNA repair; Biochemistry; Yeast; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001851223,0.0001974499,0.0002546226,0.00006795159,0.0000833001,0.00003976724,0.0002853113,0.0001354015,0.003633805],"category_scores_gemma":[0.00003261855,0.0001657619,0.0001083925,0.000139461,0.0001043303,0.00008577732,0.0001410741,0.0002529362,0.0007200428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000396075,"about_ca_system_score_gemma":0.00007641842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000111075,"about_ca_topic_score_gemma":0.00001413736,"domain_scores_codex":[0.9987988,0.0000324141,0.0003634449,0.0003481843,0.0002167099,0.0002403713],"domain_scores_gemma":[0.9989515,0.00009697516,0.0002144629,0.0005405946,0.0001019261,0.00009453909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003196263,0.0000274792,0.0002640317,0.0001530035,0.00003879944,0.000001740552,0.000175335,0.000009145178,0.9941664,0.0000579402,0.004616507,0.0004576216],"study_design_scores_gemma":[0.0008682466,0.00001638656,0.0004772971,0.00002479382,0.00009970981,0.00001679404,0.0001172543,0.0000273769,0.9744664,0.00008787281,0.02361046,0.0001874101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935138,0.0001548932,0.00005952953,0.0003511602,0.0003545217,0.0001869667,0.0004795518,0.00003358423,0.004865995],"genre_scores_gemma":[0.9758173,0.000007433297,0.0005470737,0.00005638976,0.00058449,0.000005728798,0.0007321988,0.00003972474,0.02220961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01970004,"threshold_uncertainty_score":0.997277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01261133180383623,"score_gpt":0.1993173073353234,"score_spread":0.1867059755314872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}