{"id":"W2947332097","doi":"10.1038/s41598-019-44536-1","title":"Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Qatar National Library; Tehran University of Medical Sciences and Health Services; King Saud University","keywords":"Mesenchymal stem cell; Stromal cell; Transformation (genetics); Cell biology; Computational biology; Computer science; Cancer research; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001316194,0.0001678059,0.0001685076,0.0002970228,0.0001206728,0.0002275385,0.00007005544,0.00009845102,0.001687105],"category_scores_gemma":[0.000138433,0.0001126318,0.0001801315,0.000168728,0.00009556161,0.0000625928,0.0002071445,0.0002807934,0.0005088031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001364971,"about_ca_system_score_gemma":0.0002267087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007467349,"about_ca_topic_score_gemma":0.0009371758,"domain_scores_codex":[0.9998333,0.0000220303,0.00001387529,0.00003649466,0.00006908194,0.00002517499],"domain_scores_gemma":[0.9999447,0.000008217379,0.00001750383,0.000007981089,0.000007076438,0.00001456251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001352596,0.00002575118,0.002225385,0.00002224523,0.00001293268,0.0000545048,0.00001945192,0.0001054981,0.9939283,0.00007364267,0.0001046248,0.003292399],"study_design_scores_gemma":[0.00003437942,0.0004372842,0.02866386,0.000009608273,0.00003914006,0.0006729172,0.00005902904,0.003231683,0.9599341,0.0001098604,0.00680237,0.000005771782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931791,0.0009337828,0.003003845,0.00005853126,0.00001718325,0.00003281309,0.001003972,0.0001327552,0.001638058],"genre_scores_gemma":[0.9949414,0.0004494675,0.001696294,0.00005686407,0.000004584229,0.00003368667,0.001563994,0.00002369471,0.001229902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001687105,"threshold_uncertainty_score":0.005643964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006279425157099571,"score_gpt":0.2475525618383389,"score_spread":0.2412731366812394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}