{"id":"W2947334480","doi":"10.1200/jco.2019.37.15_suppl.tps5597","title":"CALLA: Efficacy and safety of durvalumab with and following concurrent chemoradiotherapy (CCRT) versus CCRT alone in women with locally advanced cervical cancer: A phase III, randomized, double-blind, multicenter study.","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Durvalumab; Cervical cancer; Internal medicine; Clinical endpoint; Oncology; Cancer; Radiation therapy; Chemoradiotherapy; Urology; Randomized controlled trial; Nivolumab; Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001473728,0.001349026,0.002348004,0.0004402733,0.0005035002,0.000963567,0.001255666,0.002011171,0.005824533],"category_scores_gemma":[0.001322239,0.0006950645,0.001597603,0.0004283973,0.001249228,0.001011336,0.000385498,0.002866147,0.001174541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008697141,"about_ca_system_score_gemma":0.00156474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001308069,"about_ca_topic_score_gemma":0.003196264,"domain_scores_codex":[0.9994382,0.0002721998,0.0000298423,0.0001050008,0.00005835082,0.00009638203],"domain_scores_gemma":[0.9990172,0.0002102052,0.0002569911,0.00008247681,0.00004818907,0.0003847936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.952291,0.02233781,0.001236045,0.0002956014,0.0006398608,0.00003733152,0.00005804119,0.0002161509,0.005608486,0.0000748396,0.0006990849,0.01650587],"study_design_scores_gemma":[0.7812073,0.212251,0.004141623,0.00001701382,0.0004784589,0.00004709276,0.00002654582,0.0004115768,0.0007855489,0.00007881027,0.0005380507,0.00001704166],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931289,0.001584098,0.0002577179,0.0003928237,0.0001996759,0.002297953,0.0007505012,0.00007481195,0.001313486],"genre_scores_gemma":[0.9914494,0.0009277497,0.0007792033,0.0007271096,0.0002696936,0.002896606,0.0008108573,0.00001892611,0.0021204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005824533,"threshold_uncertainty_score":0.019485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05282560527458163,"score_gpt":0.4371832909920048,"score_spread":0.3843576857174232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}