{"id":"W2947495774","doi":"10.1126/sciadv.aav7999","title":"Control of antiviral innate immune response by protein geranylgeranylation","year":2019,"lang":"en","type":"article","venue":"Science Advances","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institute of Allergy and Infectious Diseases; U.S. Department of Veterans Affairs","keywords":"Innate immune system; Geranylgeranylation; Biology; Cell biology; Ubiquitin ligase; Immune system; Ubiquitin; Prenylation; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001145555,0.0001168484,0.0002386777,0.0001785317,0.000142998,0.00001648104,0.0003680949,0.00006524994,0.0002709963],"category_scores_gemma":[0.0002607284,0.00009352718,0.00005673561,0.000349228,0.0009031954,0.0006889182,0.0000441935,0.0001354348,0.0004360068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002881337,"about_ca_system_score_gemma":0.0001376007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001789719,"about_ca_topic_score_gemma":5.485786e-7,"domain_scores_codex":[0.9987804,0.0002523875,0.0002921285,0.0002665457,0.00008151199,0.0003270823],"domain_scores_gemma":[0.9992682,0.0001415051,0.0001780396,0.0002675361,0.0001340984,0.00001056514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003445643,0.00004168785,0.0005943761,0.000007914675,0.0000100245,3.145967e-7,0.0001433654,0.000004495379,0.9893589,0.000286364,0.00002594321,0.006080952],"study_design_scores_gemma":[0.001246185,0.0005409502,0.005685688,0.0000488956,0.000003250013,0.000004836717,0.0001388469,0.000009898826,0.9673605,0.00006032306,0.02478493,0.0001157222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922192,0.005591383,0.0003023233,0.0002553886,0.0005278426,0.0003688854,0.00002254199,0.00003131177,0.0006811363],"genre_scores_gemma":[0.9937323,0.0000138244,0.0000485257,0.00006351765,0.000002976184,0.00001236229,0.000004746662,0.000006107932,0.006115594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02475898,"threshold_uncertainty_score":0.5604131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004202738331015419,"score_gpt":0.247153125562781,"score_spread":0.2429503872317656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}