{"id":"W2947495925","doi":"10.1186/s12885-019-5686-1","title":"Raman spectroscopy detects metabolic signatures of radiation response and hypoxic fluctuations in non-small cell lung cancer","year":2019,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia, Okanagan Campus; University of British Columbia; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; BC Cancer Foundation","keywords":"Radiosensitivity; Radiation therapy; Hypoxia (environmental); Lung cancer; Cancer research; Medicine; Pathology; Glycolysis; Glycogen; Cancer; Biology; Internal medicine; Chemistry; Metabolism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003406679,0.0001572657,0.0003535505,0.000325114,0.0000283254,0.00001313271,0.00007158839,0.0001323083,0.0002369381],"category_scores_gemma":[0.000158355,0.0001489108,0.00006031718,0.000367382,0.0000331048,0.0001043073,0.00001942135,0.0001999741,0.000007233583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001819296,"about_ca_system_score_gemma":0.0004926474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006234035,"about_ca_topic_score_gemma":0.001145417,"domain_scores_codex":[0.9988862,0.0001272401,0.000258985,0.0002845798,0.0002187127,0.000224326],"domain_scores_gemma":[0.9990743,0.0003216925,0.0001680027,0.0002675747,0.00007592462,0.00009248806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008390828,0.00004248825,0.3571107,0.0003079467,0.0000314422,0.000001870476,0.0007193435,0.002697419,0.6364725,0.00002395062,0.0004383128,0.001314918],"study_design_scores_gemma":[0.002649493,0.0001225656,0.7333664,0.0001176974,0.00009941441,0.000001059922,0.00004382474,0.005034963,0.2580268,0.00001112757,0.0004115792,0.0001150292],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758214,0.02203341,0.0001500234,0.0002945224,0.0002798798,0.001153024,0.00002683903,0.00002525987,0.0002156367],"genre_scores_gemma":[0.9966251,0.0009348713,0.001081824,0.0002588718,0.0001607761,0.0001679518,0.000008540566,0.00003186858,0.0007302589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3784457,"threshold_uncertainty_score":0.6072406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005883287560294534,"score_gpt":0.2767117010591404,"score_spread":0.2708284134988459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}