{"id":"W2947532070","doi":"10.1016/j.biologicals.2019.05.002","title":"Octanorm [cutaquig®], a new immunoglobulin (human) subcutaneous 16.5% solution for injection (165 mg/mL) – Biochemical characterization, pathogen safety, and stability","year":2019,"lang":"en","type":"article","venue":"Biologicals","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Antibody; Immune system; Immunoglobulin G; Titer; Chemistry; Subcutaneous injection; Manufacturing process; Immunology; Medicine; Materials science; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004633571,0.0004820987,0.0002884576,0.0008618675,0.0001605463,0.0004703641,0.0003605649,0.0004518123,0.003654728],"category_scores_gemma":[0.0005203702,0.0001583888,0.0002987199,0.0003131145,0.0002652905,0.0004826707,0.0003220896,0.0006640934,0.001477038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000243417,"about_ca_system_score_gemma":0.0005031051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000593711,"about_ca_topic_score_gemma":0.0006014623,"domain_scores_codex":[0.9995771,0.00006203774,0.00003035375,0.00005449449,0.0002478373,0.00002817606],"domain_scores_gemma":[0.9998054,0.00003265166,0.00007184048,0.00001406102,0.00004154312,0.00003444932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00142026,0.0005016471,0.0014658,0.001180824,0.00007019683,0.0005288434,0.00008816242,0.0003713131,0.7401069,0.001538077,0.01055486,0.2421731],"study_design_scores_gemma":[0.0006472784,0.006891637,0.01018449,0.0005668233,0.0002102342,0.01037474,0.00007927457,0.002721787,0.6603715,0.0007692063,0.3070756,0.0001073994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6471455,0.1351471,0.1309887,0.001499966,0.001227768,0.003827526,0.005462607,0.004974111,0.06972688],"genre_scores_gemma":[0.7991571,0.04770778,0.08602785,0.00209507,0.0004437096,0.002046098,0.01762657,0.0006357533,0.04425994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003654728,"threshold_uncertainty_score":0.01222622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01298184608359994,"score_gpt":0.2285992981866764,"score_spread":0.2156174521030765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}