{"id":"W2947584576","doi":"10.1007/978-1-4939-9516-5_14","title":"Peptide-Modified Gemini Surfactants: Preparation and Characterization for Gene Delivery","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Gene delivery; Cationic polymerization; Biocompatibility; Pulmonary surfactant; Chemistry; Transfection; Genetic enhancement; Nanotechnology; Biophysics; Gene; Biochemistry; Materials science; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005456049,0.0003091941,0.0002396924,0.0003063666,0.0002778698,0.0002523147,0.0002833447,0.000359152,0.0005134637],"category_scores_gemma":[0.0006739229,0.000147635,0.0001550079,0.0005285204,0.0001931472,0.0002807378,0.0001589512,0.0005151095,0.0003314837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003291232,"about_ca_system_score_gemma":0.0003979531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008813244,"about_ca_topic_score_gemma":0.001730292,"domain_scores_codex":[0.9997181,0.00004573412,0.00002869905,0.00004326635,0.0001205481,0.0000435512],"domain_scores_gemma":[0.9996353,0.00006855738,0.00007479641,0.00003085435,0.0001347549,0.00005565941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004511279,0.00001034272,0.00008939219,0.00002617487,0.000003131681,0.0000255333,0.00002369538,0.00003557793,0.9984087,0.00006228926,0.00002097433,0.00124917],"study_design_scores_gemma":[0.000004767149,0.00006501238,0.0005366863,0.000002572084,0.000005826625,0.00008829752,0.00001151953,0.0004799774,0.9970436,0.00002259456,0.001736457,0.000002745507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9494242,0.002762505,0.04532614,0.0001823902,0.00003526298,0.0002030896,0.0003935677,0.0001607919,0.001511996],"genre_scores_gemma":[0.9333637,0.00391235,0.05545212,0.0001347022,0.00002001837,0.0001732327,0.001792567,0.0001258861,0.005025376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008813244,"threshold_uncertainty_score":0.002885461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01871987283333089,"score_gpt":0.3589180006929489,"score_spread":0.340198127859618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}