{"id":"W2947628324","doi":"10.1016/j.nbd.2019.104485","title":"Ionic and synaptic mechanisms of seizure generation and epileptogenesis","year":2019,"lang":"en","type":"review","venue":"Neurobiology of Disease","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Epileptogenesis; Neuroscience; Epilepsy; Homeostasis; Homeostatic plasticity; Status epilepticus; Traumatic brain injury; Psychology; Medicine; Neurotransmission; Psychiatry; Internal medicine; Metaplasticity; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005184322,0.001289702,0.001481079,0.001655988,0.0002851045,0.001285626,0.001189644,0.001343014,0.002612648],"category_scores_gemma":[0.0005668019,0.0002767082,0.0002962773,0.002177425,0.0009485342,0.002123774,0.0009221683,0.001839719,0.002067938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008051302,"about_ca_system_score_gemma":0.00113824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009777648,"about_ca_topic_score_gemma":0.002380676,"domain_scores_codex":[0.9999021,0.00001327386,0.00001876951,0.00001969246,0.0000333855,0.00001281408],"domain_scores_gemma":[0.9997776,0.00009777713,0.00003693072,0.000007954598,0.00005313369,0.00002654462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001359616,0.00007128232,0.0001794531,0.01345574,0.00007093951,0.0003040988,0.00007266799,0.0005543677,0.003116356,0.01141044,0.04060462,0.9300241],"study_design_scores_gemma":[0.00002208614,0.00007843012,0.001019618,0.003733524,0.00009997794,0.001306118,0.00009614968,0.0001538589,0.000532304,0.01295053,0.9799804,0.00002701953],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008896483,0.9978768,0.0001859355,0.0003110225,0.0003095749,0.000003827488,0.00001759918,0.00000618614,0.001200084],"genre_scores_gemma":[0.0004295023,0.9982906,0.0001602043,0.0001525386,0.0003387059,0.000004775507,0.00002517208,9.624951e-7,0.0005975182],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002612648,"threshold_uncertainty_score":0.008740187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1306342079899611,"score_gpt":0.3761084917230245,"score_spread":0.2454742837330634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}