{"id":"W2947696102","doi":"10.1200/jco.2019.37.15_suppl.e16518","title":"A phase II study of enzalutamide (Enz) with dutasteride (Dut) or finasteride (Fin) in men ≥ 65 years with hormone-naive systemic prostate cancer (HNSPCa): Tolerability and geriatric asssessment (GA) results.","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Tolerability; Prostate cancer; Androgen deprivation therapy; Internal medicine; Androgen deficiency; Geriatric Depression Scale; Adverse effect; Urology; Cancer; Androgen; Endocrinology; Hormone","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001784996,0.001379,0.001626912,0.0004442307,0.0003626689,0.0007913773,0.0007995474,0.0009977026,0.003489645],"category_scores_gemma":[0.000831222,0.0007013381,0.001191995,0.0004066413,0.0009080228,0.0008046156,0.0003703043,0.002242921,0.0007210418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006795776,"about_ca_system_score_gemma":0.001498298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001340899,"about_ca_topic_score_gemma":0.003454164,"domain_scores_codex":[0.9995759,0.0002145491,0.00002300654,0.00006906119,0.00003673511,0.00008079255],"domain_scores_gemma":[0.9991817,0.00009868365,0.0001631022,0.00005333788,0.00004853288,0.0004547563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7479833,0.1517441,0.009838136,0.0005609762,0.001212774,0.0001809091,0.0003138492,0.001579447,0.02989839,0.0001979114,0.00210701,0.05438334],"study_design_scores_gemma":[0.4360521,0.5461915,0.01329759,0.00002080768,0.0003065697,0.0001652507,0.00007402086,0.0006728637,0.001709164,0.0001253155,0.001361999,0.00002284311],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930891,0.001156243,0.0005283244,0.0001864627,0.00008612199,0.003059943,0.0008510058,0.0000633192,0.0009795502],"genre_scores_gemma":[0.9890431,0.001172524,0.001752698,0.00076463,0.0001389629,0.002949237,0.001897735,0.00002263649,0.002258397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003489645,"threshold_uncertainty_score":0.01167405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08323762863015056,"score_gpt":0.4713934125413345,"score_spread":0.3881557839111839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}