{"id":"W2947755685","doi":"10.1186/s12906-019-2505-9","title":"Hibiscus flower extract selectively induces apoptosis in breast cancer cells and positively interacts with common chemotherapeutics","year":2019,"lang":"en","type":"article","venue":"BMC Complementary and Alternative Medicine","topic":"Hibiscus Plant Research Studies","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Lotte and John Hecht Memorial Foundation","keywords":"Hibiscus; Breast cancer; Pharmacology; Medicine; Cancer; Cancer cell; Apoptosis; Phytochemical; Cisplatin; MCF-7; Cancer research; Traditional medicine; Estrogen receptor; Chemotherapy; Biology; Internal medicine; Biochemistry; Botany; Human breast","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005129159,0.0003039462,0.0004725969,0.0002089616,0.0001575899,0.00001591434,0.0001645388,0.00005791037,0.001806382],"category_scores_gemma":[0.000007448736,0.0002070911,0.00002168545,0.0001962909,0.0004055349,0.0001906683,0.0001499624,0.0006846932,0.000008335378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001099021,"about_ca_system_score_gemma":0.00004701605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001362906,"about_ca_topic_score_gemma":0.00181127,"domain_scores_codex":[0.9981578,0.0003881177,0.0003061309,0.0004374322,0.000256869,0.0004536699],"domain_scores_gemma":[0.9986883,0.000816147,0.0001350397,0.0000930754,0.00009276758,0.0001746655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002442414,0.0003095042,0.7547895,0.0001703135,0.0006307515,0.00003921681,0.005661257,0.00005136567,0.223851,0.00007958602,0.00101326,0.01096181],"study_design_scores_gemma":[0.01319093,0.001376317,0.7598957,0.0006895388,0.0002447976,0.000119106,0.004568639,0.001930777,0.2101023,0.0001233153,0.007134415,0.000624243],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939039,0.0006787718,0.00002209209,0.002993128,0.0002677834,0.0007479932,0.0003737732,0.00001964675,0.0009929581],"genre_scores_gemma":[0.9960395,0.001518816,0.0001145607,0.001809193,0.0001896566,0.00004839974,0.00004408149,0.00001923432,0.0002166316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01374871,"threshold_uncertainty_score":0.9991061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1085185930793677,"score_gpt":0.4407913404284418,"score_spread":0.3322727473490741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}