{"id":"W2947759939","doi":"10.1002/ptr.6378","title":"<scp><i>Lathyrus sativus</i></scp> diamine oxidase counteracts histamine‐induced cell proliferation, migration and pro‐angiogenic mediators release in human colon adenocarcinoma cell line Caco‐2","year":2019,"lang":"en","type":"article","venue":"Phytotherapy Research","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Regione Lazio; Public Health England","keywords":"Histamine; Diamine oxidase; Biology; Histamine H2 receptor; Cell growth; Cell biology; Endocrinology; Biochemistry; Chemistry; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005729405,0.0002510049,0.0002592197,0.0002648463,0.0001645916,0.00008007165,0.0002641017,0.0002027133,0.00002044329],"category_scores_gemma":[0.00009998483,0.0002442977,0.00006847094,0.0003922687,0.00009709306,0.00002614606,0.00008844195,0.0003024996,0.00003903744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005260562,"about_ca_system_score_gemma":0.000205886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003056564,"about_ca_topic_score_gemma":0.0007343229,"domain_scores_codex":[0.9977424,0.0002650541,0.0003758785,0.0006625141,0.0004140078,0.0005401417],"domain_scores_gemma":[0.998727,0.0001071869,0.0001286927,0.0005716078,0.0002669023,0.0001985798],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006458739,0.0003677604,0.02590927,0.00006847137,0.00001459147,0.000004271516,0.0006387861,0.000009401897,0.9708856,0.00003568655,0.001670782,0.0003308065],"study_design_scores_gemma":[0.002205833,0.0006843039,0.03364814,0.0000148765,0.000009825126,0.000003260313,0.0001797653,0.0002674501,0.9404831,0.00006994962,0.02228936,0.0001441501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903056,0.007329417,0.00003078679,0.0002351731,0.00006297084,0.001494201,0.00006717294,0.00001752626,0.0004571296],"genre_scores_gemma":[0.991529,0.001172498,0.00009679866,0.0001549512,0.0003944536,0.0004302498,0.0005048626,0.00005937492,0.005657844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0304025,"threshold_uncertainty_score":0.996217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02118159056631334,"score_gpt":0.3065707606412154,"score_spread":0.285389170074902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}