{"id":"W2947760688","doi":"10.1136/jnnp-2019-320846","title":"Orthostatic hypotension and REM sleep behaviour disorder: impact on clinical outcomes in α-synucleinopathies","year":2019,"lang":"en","type":"review","venue":"Journal of Neurology Neurosurgery & Psychiatry","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Synucleinopathies; Dementia with Lewy bodies; Pure autonomic failure; Orthostatic vital signs; Dementia; Cognition; Medicine; Lewy body; Psychology; REM sleep behavior disorder; Rapid eye movement sleep; Atrophy; Physical medicine and rehabilitation; Parkinson's disease; Internal medicine; Neuroscience; Disease; Eye movement; Alpha-synuclein; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008162323,0.0008332951,0.005088476,0.001204971,0.00007238518,0.00003587495,0.0002082266,0.0006638673,0.00003411457],"category_scores_gemma":[0.0004416998,0.0005294906,0.002434797,0.0003275614,0.0001180886,0.0001188654,0.00009378087,0.002416507,0.00004827831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004165778,"about_ca_system_score_gemma":0.0006890998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006815401,"about_ca_topic_score_gemma":0.0000044726,"domain_scores_codex":[0.9944499,0.001131157,0.00259276,0.0007714298,0.0005104009,0.0005443697],"domain_scores_gemma":[0.9952303,0.001295649,0.00222417,0.0006660021,0.00009683106,0.0004870095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001085856,0.002080744,0.8400425,0.001241953,0.0004419108,0.005194085,0.000005136355,0.0000028959,3.025965e-7,0.00000663756,0.0006633509,0.1492346],"study_design_scores_gemma":[0.002430678,0.007945024,0.8932633,0.002810182,0.003927333,0.006960909,0.000003904176,0.000007363406,3.679668e-8,0.00007223959,0.08224867,0.0003303617],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5071788,0.4874888,7.862677e-7,0.0006655059,0.004122957,0.000477418,0.00004023867,0.00001511122,0.00001040067],"genre_scores_gemma":[0.04842581,0.9486039,0.00007079019,0.002408351,0.0002771997,0.00001071231,0.00001784058,0.0001453679,0.00003998721],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.4611152,"threshold_uncertainty_score":0.999885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05308327466974695,"score_gpt":0.3799285506962072,"score_spread":0.3268452760264603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}