{"id":"W2947827172","doi":"10.1002/mrd.23173","title":"Functional importance of palmitoyl protein thioesterase 1 (PPT1) expression by Sertoli cells in mediating cholesterol metabolism and maintenance of sperm quality","year":2019,"lang":"en","type":"article","venue":"Molecular Reproduction and Development","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vector Institute","funders":"Science and Technology Commission of Shanghai Municipality; National Natural Science Foundation of China","keywords":"Biology; Sertoli cell; Thioesterase; Sperm; Sperm quality; Cell biology; Metabolism; Biochemistry; Spermatogenesis; Endocrinology; Enzyme; Genetics; Biosynthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001065708,0.0001990284,0.0001554292,0.0001653307,0.0001637076,0.0002048473,0.0001251523,0.0002674252,0.001458341],"category_scores_gemma":[0.0001025074,0.00008240902,0.0001878302,0.00009397735,0.0002173616,0.0002075116,0.000151989,0.000283035,0.0002756082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000164843,"about_ca_system_score_gemma":0.0002117973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004545494,"about_ca_topic_score_gemma":0.0006381469,"domain_scores_codex":[0.9999298,0.00001548478,0.00000721114,0.00001592393,0.00001745416,0.0000142582],"domain_scores_gemma":[0.9999168,0.000009614521,0.00002198464,0.000006169635,0.00001549278,0.00003004113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008153344,0.000007453318,0.0007390818,0.00005481314,0.000004809585,0.0001181416,0.00001772705,0.00003281065,0.9974923,0.000134695,0.00003273788,0.001283936],"study_design_scores_gemma":[0.00002525377,0.0003430687,0.0388134,0.00001585706,0.00004325364,0.001229772,0.0001261827,0.0009849565,0.95437,0.0001916531,0.003848589,0.000008082297],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902208,0.004972517,0.00290012,0.0002360932,0.00003677248,0.00001446552,0.0002699952,0.00005391314,0.001295296],"genre_scores_gemma":[0.994655,0.001851366,0.0009953514,0.00005033479,0.00001090146,0.00001044251,0.0003292721,0.000007770645,0.002089596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001458341,"threshold_uncertainty_score":0.00487864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01281911064854703,"score_gpt":0.2396348490998381,"score_spread":0.226815738451291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}